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儿童社区获得性肺炎病原学回顾性研究 被引量:2

A Retrospective Study of the Etiology of Childhood Community-acquired Pneumonia
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摘要 目的:探究儿童社区获得性肺炎病原学检测结果及临床症状特点。方法:本次研究采用回顾性分析法,选取2018年10月1日-2019年10月31日诊断为儿童社区获得性肺炎的2 549例患儿为研究对象,依据年龄阶段,将其分为<1岁患儿985例,1~3岁患儿753例,4~6岁患儿811例,均接受酶联免疫吸附剂测定(ELISA)检测患儿呼吸道分泌物呈7种常见的呼吸道病毒抗原,分别为腺病毒、呼吸道合胞病毒、流感病毒A、流感病毒B、副流感病毒Ⅰ、Ⅱ、Ⅲ型。结果:<1岁患儿、1~3岁患儿均为呼吸道合胞病毒检出率最高,4~6岁患儿流感病毒A检出率最高,<1岁患儿腺病毒、副流感病毒Ⅲ型检出率并列第二,1~3岁患儿、4~6岁患儿均为腺病毒检出率第二。在临床症状表现方面,主要症状为发热、咳嗽、气喘、肺部啰音等,伴有结膜充血、呼吸衰竭、心力衰竭等症状,其中,发热患儿517例,占比20.28%;咳嗽患儿371例,占比14.55%;气喘患儿451例,占比17.69%;肺部啰音患儿417例,占比16.36%;出现较少的结膜充血患儿195例,占比7.65%,呼吸衰竭患儿135例,占比5.30%;心力衰竭患儿15例,占比0.58%。所有临床症状中合胞病毒检出率最高。结论:在儿童时期的获得性肺炎中病毒感染较为常见,病毒感染引起社区获得性肺炎的主要致病原因多为呼吸道合胞病毒,在患病儿童年龄中,<1岁的儿童发病较多。 Objective:To explore the etiological detection results and clinical characteristics of children’s community-acquired pneumonia.Method:A retrospective analysis was used in this study to study,2 549 children diagnosed with community-acquired pneumonia from October 1,2018 to October 31,2019 were selected.According to the age stage,the patients were divided into < 1 year old with 985 children,1-3 years old with 753 children,and 4-6 years old with 811 children.All of them were detected by enzyme-linked immunosorbent assay (ELISA).Seven kinds of common respiratory virus antigens were detected in the respiratory secretion of the children,which were adenovirus,respiratory syncytial virus,influenza virus A,influenza virus B,parainfluenza virus Ⅰ,Ⅱ,Ⅲ type.Result:The highest detection rates of respiratory syncytial virus were found in children < 1 year old,1-3 years old,the highest detection rate of influenza virus A was found in in children aged 4-6 years old,< 1 year old children adenovirus,parainfluenza Ⅲ type tied for second detection rate,the second highest adenovirus detection rate was found in children aged 1-3 years and 4-6 years.In terms of clinical symptoms,the main symptoms were fever,cough,asthma,lung rales,accompanied by conjunctival congestion,respiratory failure,heart failure and other symptoms.There were 517 children with fever,accounting for 20.28%,371 children with cough,accounting for 14.55%,451 children with asthma,accounting for 17.69%,417 children with lung rales,accounting for 16.36%,195 children with conjunctival congestion,accounting for 7.65%,135 children with respiratory failure,accounting for 5.30%,15 children with heart failure,accounting for 0.58%.Syncytial virus was detected at the highest rate among all clinical symptoms.Conclusion:In childhood acquired pneumonia,viral infection is relatively common,and the main pathogenic cause of community-acquired pneumonia caused by viral infection is mostly respiratory syncytial virus.In the age of infected children,children < 1 year old have m
作者 林雅璇 陆妹 LIN Yaxuan;LU Mei(Women and Children’s Hospital Affiliated to Xiamen University,Xiamen 361000,China)
出处 《中外医学研究》 2020年第27期60-62,共3页 CHINESE AND FOREIGN MEDICAL RESEARCH
基金 厦门市医疗卫生指导性项目(3502z20199078)。
关键词 儿童社区获得性肺炎 病原学检测 临床特点 Community-acquired pneumonia in children Etiological detection Clinical characteristics
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