摘要
目的:调查广州市南沙区儿童社区获得性肺炎的病原体种类及临床特征。方法:纳入2015年10月~2017年1月确诊为社区获得性肺炎的患儿207例,按照年龄不同分为4个组别,分别为<1岁年龄组、1~3岁年龄组、4~6岁年龄组及>6岁年龄组。检测患儿感染的病原体并进行药敏试验,比较各组和不同季节的病原体感染情况差异,观察不同病原体感染的临床特点。结果:①病原体分布:207例患儿,总检出率病原体为174株(84.1%),其中细菌61株(29.5%),病毒42株(20.3%),肺炎支原体59株(28.5%)和肺炎衣原体12株(5.8%)。②年龄段病原体特点:<1岁患儿病毒感染的比例高于其他年龄段,而7~14岁患儿肺炎衣原体感染的比例高于其他年龄段。4~6岁患儿肺炎支原体检出率较高(47.2%),而细菌的检出率低(16.7%)。各病原体在不同季度检出比较差异无统计学意义(P>0.05)。③耐药性:对于4种主要的病原菌金黄色葡萄球菌、肺炎链球菌、肺炎克雷伯菌、大肠埃希菌,除万古霉素外,各种抗菌药均有耐药存在,亚胺培南和阿莫西林/棒酸的耐药性较低,氨苄西林和青霉素有较高的耐药性。④临床特征:细菌感染病例发热多见,肺部湿性啰音较明显;病毒感染<1岁婴幼儿常见,多有咳嗽,呼吸加快;肺炎支原体感染患儿病程较长,以咳嗽、咳痰为主。结论:广州市南沙区CAP患儿感染病原在不同年龄段和各季度均呈散在分布,但其临床特点缺乏特征性,应重视和加强对儿童CAP病原学、流行病学的监测及临床特点的研究。
Objective To investigate the pathogens and clinical characteristics of children′s community acquired pneumonia in Nansha District of Guangzhou City.Method 207 children diagnosed with community-acquired pneumonia from October 2015 to January 2017 were divided into 4 groups according to age,namely<1 year old group,1~3 years old age group,4~6 Age group and>6 age group.The pathogens of the infected children were tested and tested for drug susceptibility.The differences in pathogen infection between groups and different seasons were compared,and the clinical features of different pathogen infections were observed.Results①Distribution of pathogens:207 cases of children,the total detection rate of pathogens was 174(accounting for 84.1%).Among them,61 strains(29.5%),42 strains(20.3%),59 strains of Mycoplasma pneumoniae(28.5%)and 12 strains of Chlamydia pneumoniae(5.8%).②Characteristics of pathogens in the age group:The proportion of viral infections in children<1 year old was higher than that in other age groups,and the proportion of Chlamydia pneumoniae infection in children aged 7~14 was higher than other age groups.The detection rate of Mycoplasma pneumoniae was higher in children 4~6 years old(47.2%),while the detection rate of bacteria was low(16.7%).There was no significant difference in the detection of pathogens in different quarters(P>0.05).③Drug resistance:for the four major pathogens Staphylococcus aureus,Streptococcus pneumoniae,Klebsiella pneumoniae,Escherichia coli,in addition to vancomycin,all kinds of antibacterial drugs were resistant,sub Amepnan had lower drug resistance,and ampicillin and penicillin had higher drug resistance.④Clinical features:cases of bacterial infections were more common,and the wetness of the lungs was more obvious;viral infections were common in infants and young children<1 year old,with more cough and faster breathing;children with mycoplasma pneumoniae had a longer course of disease,coughing mainly.Conclusion The pathogens of children with CAP in Nansha District of Gua
作者
彭惠轩
杜玉萍
夏厚才
罗小兵
PENG Hui-xuan;DU Yu-ping;XIA Hou-cai(The Sixth People′s Hospital of Nansha District,Guangzhou City,Guangzhou 511470,China)
出处
《吉林医学》
CAS
2019年第12期2832-2835,共4页
Jilin Medical Journal
基金
广州市南沙区科技计划项目[项目编号:2015MS016]
关键词
社区获得性肺炎
儿童
病原体
临床特征
Community acquired pneumonia
Children
Pathogens
Clinical features
