摘要
为探究一种生成单个液滴周期短、消耗连续相试剂量小、加工成本低的微流控芯片,利用FLUENT仿真软件和VOF方法对正交试验中16种不同结构尺寸的微流控芯片进行数值模拟,最后,使用理想解法(TOPSIS)对数值模拟结果进行综合评价,得出16种结构的优劣次序。评价结果表明,当连续相通道尺寸为40μm、离散相通道尺寸为30μm、十字出口通道尺寸为25μm、通道深度为20μm时,可以得到尺寸结构最优的微流控芯片。该微流控芯片生成微滴直径较小,生成频率最高,单位时间内消耗连续相试剂较少。
This study aimed to explore a microfluidic chip that could generate a single droplet with a short cycle,consume a small amount of continuous phase reagents,and have low processing costs.The FLUENT simulation and VOF method were employed to simulate 16 microfluidic chips with different structure sizes in orthogonal experiments.Finally,the TOPSIS was used to comprehensively evaluate the numerical simulation results,and the order of superiority and inferiority of 16 structures was obtained.The evaluation results showed that a microfluidic chip with the optimal size structure could be obtained under the conditons of the continuous phase channel size was 40μm,the discrete phase channel size was 30μm,the cross exit channel size was 25μm and the channel depth was 20μm.The microfluidic chip could be produced the performance with smaller droplets,highest frequency and consumes less continuous phase reagent per unit time.
作者
徐刚
梁帅
刘武发
郑鹏
XU Gang;LIANG Shuai;LIU Wufa;ZHENG Peng(School of Mechanical and Power Engineering,Zhengzhou University,Zhengzhou 450001,China;Guangdong Shunde Innovation Design Institute,Foshan 528311,China)
出处
《郑州大学学报（工学版）》
CAS
北大核心
2020年第4期87-91,共5页
Journal of Zhengzhou University（Engineering Science）
基金
国家自然科学基金资助项目(51775515)。
