摘要
目的探讨多囊卵巢综合征患者子宫内膜厚度与血清抗苗勒氏管激素(AMH)及糖脂代谢指标水平的相关性。方法选取2016年6月至2017年12月本院收治的80例多囊卵巢综合征患者为研究组,另选取96例同期体检健康女性为对照组。研究对象均进行子宫内膜厚度、血清AMH及代谢相关指标[空腹血糖(FPG),空腹胰岛素(FINS)、甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白(HDL)、低密度脂蛋白(LDL)]水平检测。比较两组的子宫内膜厚度、血清AMH及代谢相关指标水平;分析研究组患者子宫内膜厚度与血清AMH及代谢相关指标水平的相关性。结果研究组子宫内膜厚度大于对照组,血清AMH水平高于对照组(P<0.05)。研究组的FPG、FINS、TG、TC及LDL水平均明显高于对照组,HDL水平明显低于对照组(P<0.05)。经Pearson相关性分析,多囊卵巢综合征患者子宫内膜厚度与血清AMH、FINS、TG、TC、LDL水平呈正相关,与HDL水平呈负相关(P<0.05),与FPG水平无相关性(P>0.05)。结论多囊卵巢综合征患者子宫内膜厚度及血清FPG、FINS、TG、TC及LDL水平均升高,HDL水平降低,且子宫内膜厚度与血清AMH、FINS、TG、TC、LDL水平关系密切,提示临床工作者在常规促排卵等治疗的同时,需积极控制血清AMH、FINS水平,调节血脂代谢,以提高治疗效果。
Objective To investigate the correlation between endometrial thickness and serum anti-Mullerian hormone(AMH),glycolipid metabolism indexes levels in patients with polycystic ovary syndrome.Methods Eighty patients with polycystic ovary syndrome admitted in the hospital from June 2016 to December 2017 were selected as study group,and another 96 healthy women through physical examination were selected as control group at the same period.The endometrial thickness,serum AMH and metabolic related indexes[fasting blood glucose(FPG),fasting insulin(FINS),triglyceride(TG),total cholesterol(TC),high density lipoprotein(HDL),low density lipoprotein(LDL)]levels of the study objects were measured.The endometrial thickness,serum AMH and metabolism related indexes levels were compared between the two groups;the correlation between endometrial thickness and serum AMH and metabolism related indexes levels of patients in the study group were analyzed.Results The endometrial thickness of the study group was larger than that of the control group,and the serum AMH level of the study group was higher than that of the control group(P<0.05).The levels of FPG,FINS,TG,TC and LDL of the study group were significantly higher than those of the control group,and the HDL level of the study group was significantly lower than that of the control group(P<0.05).Pearson correlation analysis showed that endometrial thickness of polycystic ovary syndrome patients were positively correlated with serum AMH,FINS,TG,TC and LDL levels,endometrial thickness was negatively correlated with HDL level(P<0.05),and endometrial thickness was no correlation with FPG level(P>0.05).Conclusion The endometrial thickness and the levels of serum AMH,FPG,FINS,TG,TC,LDL and HDL of polycystic ovary syndrome patients are increased,while HDL level is decreased,and the endometrial thickness of patients are closely related to the levels of serum AMH,FINS,TG,TC,LDL and HDL.It suggested that at the same time of routine ovulation induction and other treatments,clinical workers sh
作者
李丹萍
张丽霞
LI Danping;ZHANG Lixia(Yellow River Sanmenxia Hospital,Sanmenxia 472000,China)
出处
《临床医学研究与实践》
2020年第27期131-133,共3页
Clinical Research and Practice
关键词
多囊卵巢综合征
子宫内膜厚度
抗苗勒氏管激素
代谢指标
polycystic ovary syndrome
endometrial thickness
anti-Mullerian hormone
metabolic indexes
