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小剂量依托咪酯复合丙泊酚在老年患者无痛胃镜检查中的应用效果 被引量:5

Application effect of low-dose etomidate combined with propofol in painless gastroscopy of elderly patients
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摘要 目的探讨小剂量依托咪酯复合丙泊酚在老年患者无痛胃镜检查中的应用效果。方法将行无痛胃镜检查的120例老年患者随机分为对照组与观察组,每组60例。对照组采用丙泊酚麻醉,观察组在对照组基础上予以小剂量依托咪酯,比较两组的麻醉效果。结果T2、T3、T4时,观察组的皮质醇、醛固酮、血糖水平均低于对照组(P<0.05)。观察组的呼吸抑制、注射痛发生率低于对照组(P<0.05)。结论小剂量依托咪酯复合丙泊酚可减轻老年患者无痛胃镜检查中的机体应激反应,减少不良反应,安全可靠。 Objective To explore the application effect of low-dose etomidate combined with propofol in painless gastroscopy of elderly patients.Methods A total of 120 elderly patients undergoing painless gastroscopy were randomly divided into control group and observation group,with 60 cases in each group.The control group was anesthetized with propofol,and the observation group was given low-dose of etomidate on the basis of the control group.The anesthetic effects of the two groups were compared.Results At T2,T3 and T4,the levels of cortisol,aldosterone and blood sugar in the observation group were lower than those in the control group(P<0.05).The incidences of respiratory depression and injection pain in the observation group were lower than those in the control group(P<0.05).Conclusion Low-dose etomidate combined with propofol can reduce the body's stress response in painless gastroscopy of elderly patients and adverse reactions,and it is safe and reliable.
作者 任学军 吕志峰 李芳坤 梁冰 朱建坡 张虎 方洁 REN Xuejun;LYU Zhifeng;LI Fangkun;LIANG Bing;ZHU Jianpo;ZHANG Hu;FANG Jie(Anesthesiology Department,the First Affliated Hospital of Henan University of CM,Zhengzhou 450000,China)
出处 《临床医学研究与实践》 2020年第27期108-109,共2页 Clinical Research and Practice
关键词 依托咪酯 丙泊酚 无痛胃镜 etomidate propofol painless gastroscopy
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