摘要
目的比较血脂康胶囊与阿托伐他汀钙片治疗老年腔隙性脑梗死伴高脂血症、高血压前期患者的临床效果。方法选取我院收治的84例老年腔隙性脑梗死伴高脂血症、高血压前期患者进行回顾性研究,根据治疗药物不同分为对照组(42例,阿托伐他汀钙片治疗)和观察组(42例,血脂康胶囊治疗)。比较两组治疗前、后的血清炎性因子水平、血脂水平及血压变化情况。结果治疗后,两组的Cys-C、Hcy、TNF-α、hs-CRP水平、SBP、DBP均降低,且观察组明显低于对照组(P<0.05)。治疗后,两组的TC、TG、LDL-C水平均降低,HDL-C水平均升高(P<0.05),但组间比较,差异无统计学意义(P>0.05)。结论血脂康胶囊与阿托伐他汀钙片治疗老年腔隙性脑梗死伴高脂血症、高血压前期患者均可有效改善患者血脂水平,且调脂效果相当,但血脂康胶囊能够更有效地改善患者血清炎性因子水平,降低血压,治疗效果优于阿托伐他汀钙片。
Objective To compare the clinical effect of Xuezhikang capsule and atorvastatin calcium tablets in the treatment of senile lacunar infarction with hyperlipidemia and prehypertension.Methods A total of 84 elderly patients with lacunar infarction,hyperlipidemia and prehypertension admitted in our hospital were retrospectively studied.According to the different treatment drugs,the patients were divided into control group(42 cases,atorvastatin calcium tablets treatment)and observation group(42 cases,Xuezhikang capsule treatment).The levels of serum inflammatory factors,blood lipid and blood pressure were compared between the two groups before and after treatment.Results After treatment,Cys-C,Hcy,TNF-α,hs-CRP levels,SBP and DBP in the two groups decreased,and those in the observation group were significantly lower than the control group(P<0.05).After treatment,the levels of TC,TG and LDL-C in the two groups decreased,while HDL-C level increased(P<0.05),but there were no significant differences between the two groups(P>0.05).Conclusion Xuezhikang capsule and atorvastatin calcium tablets in the treatment of senile lacunar infarction with hyperlipidemia and prehypertension can effectively improve the blood lipid levels of patients,and the effect of lipid regulation is similar.But Xuezhikang capsule can more effectively improve the levels of serum inflammatory factors,reduce blood pressure,and its treatment effect is better than atorvastatin calcium tablets.
作者
岳龙华
YUE Longhua(Xi'an No.1 Hospital,Xi'an 710000,China)
出处
《临床医学研究与实践》
2020年第27期16-17,22,共3页
Clinical Research and Practice
