摘要
目的对比分析阿奇霉素与红霉素治疗小儿支原体肺炎的临床疗效。方法111例小儿支原体肺炎患儿,根据用药不同分为阿奇霉素组(56例)和红霉素组(55例)。阿奇霉素组应用阿奇霉素治疗,红霉素组应用红霉素治疗,对比两组患儿临床疗效、临床症状消失时间及不良反应发生情况。结果阿奇霉素组总有效率为96.43%,高于红霉素组的80.00%,差异具有统计学意义(P<0.05)。阿奇霉素组患儿湿啰音、咳嗽、发热消失时间分别为(4.50±1.37)、(3.20±0.41)、(1.69±0.17)d,均短于红霉素组的(7.11±1.65)、(5.69±0.70)、(3.48±0.28)d,差异均具有统计学意义(P<0.05)。阿奇霉素组用药不良反应发生率为3.57%,低于红霉素组的18.18%,差异具有统计学意义(P<0.05)。结论阿奇霉素治疗小儿支原体肺炎的临床效果显著,并且临床症状消失时间较红霉素更短,是一种优秀的抗菌药物。
Objective To compare the clinical efficacy of azithromycin and erythromycin in the treatment of mycoplasma pneumonia in children.Methods A total of 111 children with mycoplasma pneumonia were divided into azithromycin group(56 cases)and erythromycin group(55 cases).Azithromycin group was treated with azithromycin,and erythromycin group was treated with erythromycin.The clinical efficacy,disappearance time of clinical symptoms and occurrence of adverse reactions were compared between the two groups.Results The total effective rate of azithromycin group was 96.43%,which was higher than that of erythromycin group 80.00%,and the difference was statistically significant(P<0.05).The disappearance time of moist rales,cough,and fever of azithromycin group were(4.50±1.37),(3.20±0.41)and(1.69±0.17)d,which were shorter than those of erythromycin group(7.11±1.65),(5.69±0.70)and(3.48±0.28)d,and the difference was statistically significant(P<0.05).The incidence of adverse reactions of azithromycin group was 3.57%,which was lower than that of erythromycin group 18.18%,and the difference was statistically significant(P<0.05).Conclusion Azithromycin has significant clinical effect in the treatment of mycoplasma pneumonia in children,and the disappearance time of clinical symptoms is shorter than that of erythromycin.
作者
徐鹤
孙晓鸥
XU He;SUN Xiao-ou(Liaoyang County Central Hospital,Liaoyang 111200,China)
出处
《中国现代药物应用》
2020年第18期111-113,共3页
Chinese Journal of Modern Drug Application
关键词
小儿支原体肺炎
阿奇霉素
红霉素
临床效果
临床症状消失时间
Mycoplasma pneumonia in children
Azithromycin
Erythromycin
Clinical effect
Disappearance time of clinical symptoms
