摘要
目的探讨血浆白蛋白(Alb)、血小板计数(PLT)及降钙素原(PCT)联合检测在肺结核诊断中的应用价值。方法收集2019年1—12月广州市增城区人民医院感染科收治的134例肺结核住院患者及疑似患者的临床资料,按照痰结核杆菌涂片镜检结果不同将患者分为痰涂片阴性组(63例)和痰涂片阳性组(71例)。检测两组患者的Alb、PLT及PCT水平,分析并比较上述指标的变化情况。结果痰涂片阳性组患者血浆Alb水平明显低于痰涂片阴性组(g/L:32.17±5.53比33.93±5.53,P<0.05),PLT和PCT与痰涂片阴性组比较差异均无统计学意义〔PLT(×10^9/L):327.25±118.53比321.94±121.76,PCT(μg/L):0.97±3.85比0.98±4.24,均P>0.05〕;痰涂片阳性组较入院时血浆Alb降低患者比例和PLT升高患者比例均明显高于痰涂片阴性组〔Alb降低比例:76.1%(54/71)比57.1%(36/63),PLT升高比例:77.5%(55/71)比54.0%(34/63),均P<0.05〕,痰涂片阳性组与痰涂片阴性组PCT升高患者比例比较差异无统计学意义〔52.1%(37/71)比52.4%(33/63),P>0.05〕。结论诊断肺结核时,可将血浆Alb和PLT水平作为有效指标,而血浆PCT虽可提示患者细菌感染情况,并不密切关联结核杆菌感染。
Objective To explore the application value of combined detection of serum albumin(Alb),platelet count(PLT)and procalcitonin(PCT)in the diagnosis of pulmonary tuberculosis.Methods The clinical data of 134 inpatients and suspected patients with pulmonary tuberculosis in Zengcheng People's Hospital during January to December 2019 were collected.According to the different results of sputum smear microscopic examination of Mycobacterium tuberculosis,the patients were divided into two groups such as sputum smear negative group(63 cases)and sputum smear positive group(71 cases).The levels of serum Alb,PLT and PCT in two groups of patients were measured,and the changes of above indexes were analyzed and compared.Results The level of serum Alb in sputum smear positive group was significantly lower than that in sputum smear negative group(g/L:32.17±5.53 vs.33.93±5.53,P<0.05),and there were no significant differences in PLT and PCT levels between sputum smear positive group and sputum smear negative group[PLT(×10^9/L):327.25±118.53 vs.321.94±121.76,PCT(μg/L):0.97±3.85 vs.0.98±4.24,both P>0.05].The proportions of patients with decreased Alb and increased PLT in sputum smear positive group were significantly higher than those in sputum smear negative group[Alb decreased ratio:76.1%(54/71)vs.57.1%(36/63),PLT increased ratio:77.5%(55/71)vs.54.0%(34/63),both P<0.05].There was no significant difference in the proportion of patients with elevated PCT between sputum smear positive group and sputum smear negative group[52.1%(37/71)vs.52.4%(33/63),P>0.05].Conclusion The levels of serum Alb and PLT can be used as effective indexes in the diagnosis of pulmonary tuberculosis,while plasma PCT can indicate the bacterial infection of patients,it is not closely related to the infection of tuberculosis.
作者
曾跃彬
姚叶萍
邓永佳
Zeng Yuebin;Yao Yeping;Deng Yongjia(Department of Infectious Diseases,Zengcheng People's Hospital,Guangzhou 511300,Guangdong,China)
出处
《实用检验医师杂志》
2020年第3期147-149,共3页
Chinese Journal of Clinical Pathologist
关键词
血浆白蛋白
血常规
降钙素原
肺结核
Plasma albumin
Blood routine
Procalcitonin
Tuberculosis
