摘要
目的:探讨联用泮托拉唑与奥曲肽治疗急性非静脉曲张性上消化道出血的临床效果。方法:选择2016年1月至2018年10月期间红河州滇南中心医院收治的88例急性非静脉曲张性上消化道出血患者作为研究对象。将这88例患者分为常规组(n=44)和试验组(n=44)。对两组患者均进行补液、止血、输血等常规治疗。在此基础上,为常规组患者使用泮托拉唑进行治疗,为试验组患者联用泮托拉唑与奥曲肽进行治疗。然后,比较两组患者住院的时间、止血的时间、输血量及其上消化道的再出血率。结果:治疗后,与常规组患者相比,试验组患者住院的时间、止血的时间均更短,其输血量更少,其上消化道的再出血率更低,差异有统计学意义(P<0.05)。结论:联用泮托拉唑与奥曲肽治疗急性非静脉曲张性上消化道出血的临床效果确切,可有效地缩短患者住院的时间。
Objective:To investigate the clinical effect of pantoprazole combined with octreotide in the treatment of acute non-varicose upper gastrointestinal bleeding.Methods:From January 2016 to October 2018,88 patients with acute non-varicose upper gastrointestinal hemorrhage admitted to Yunnan Central Hospital in Honghe Prefecture were selected as study subjects.The 88 patients were divided into the conventional group(n=44)and the experimental group(n=44).The two groups of patients were treated with fluid infusion,hemostasis,blood transfusion and other routine treatments.On this basis,patients in the conventional group were treated with pantoprazole,and patients in the experimental group were treated with pantoprazole combined with octreotide.Then,the duration of hospitalization,duration of hemostasis,volume of blood transfusion,and rebleeding rate of upper gastrointestinal tract were compared between the two groups.Results:After treatment,compared with the conventional group,the experimental group patients had shorter hospitalization time,shorter hemostasis time,less blood transfusion volume,and lower rebleeding rate of upper gastrointestinal tract,with statistically significant differences(P<0.05).Conclusion:Pantoprazole combined with octreotide is effective in the treatment of acute non-varicose upper gastrointestinal bleeding and can effectively shorten the length of hospital stay.
作者
潘蔚竑
Pan Weihong(Honghe Zhou Yunnan Central Hospital,Honghe 661000,China)
关键词
泮托拉唑
奥曲肽
急性非静脉曲张上消化道大出血
Pantoprazole
Mr Qu peptide
Acute non-varicose upper gastrointestinal massive hemorrhage
