摘要
目的评估全调节缝线法在小梁切除术治疗原发性开角型青光眼(POAG)的应用价值。方法纳入POAG患者55例(61只眼),分为2组:全调节缝线组26例(31只眼),部分调节缝线组29例(30只眼),分别给予小梁切除手术配合不同的调节缝线,观察术后前房、滤过泡的情况,和术后6个月眼压的情况。结果 (1)术后眼压:试验组和对照组患者术后眼压比较,在7 d(t=-2.197,P=0.032)、3个月(t=-2.040,P=0.046)及6个月(t=-2.054,P=0.044),均有统计学意义(P<0.05);(2)术后并发症:试验组术后浅前房的发生率(浅I级6.45%;浅III级3.23%)低于对照组(浅I级13.33%;浅III级10.00%),但两组之间无统计学意义(P>0.05);(3)术后6个月滤泡形态:试验组I型滤泡的比例(64.52%)高于对照组(33.33%),有统计学意义(x^2=5.931,P=0.015),但试验组总体功能性滤泡(I型+Ⅱ型)的比例与对照组比较,无统计学意义(x^2=1.828,P=0.176);(4)术后6个月手术成功率:试验组总成功率96.77%(30例),而对照组86.67%(26例)。但是2组比较,无统计学意义(P>0.05);(5)其它:术后使用降眼压药及再次手术情况,2组比较均无统计学意义(P>0.05)。结论全调节缝线小梁切除术组在术后降低眼压效果、降低术后浅前房等方面优于部分调节缝线小梁切除术组,可以提高手术成功率,值得临床推广。
OBJECTIVE To evaluate the application value of total adjustable suture in trabeculectomy for primary open angle glaucoma(POAG). METHODS Fifty-five patients(61 eyes)with POAG from the department of glaucoma of Eye Hospital, China Academy of Chinese Medical Sciences were divided into two groups, with 26 patients(31 eyes) in the fully regulated suture group and 29 patients(30 eyes) in the partially regulated suture group. Trabeculectomy was performed with different adjusting sutures. The condition of anterior chamber, filtering bleb and intraocular pressure were observed 6 months after operation. RESULTS(1) Postoperative intraocular pressure: compared with the two groups, the postoperative intraocular pressure was of statistically significance at 7 d(t=-2.197, P=0.032), 3 months(t=-2.040, P=0.046) and 6 months(t=-2.054,P=0.044);(2) Postoperative complications: the incidence of postoperative shallow anterior chamber in the experimental group(6.45% of shallow grade I and 3.23% of shallow grade III) was lower than that of the control group(13.33% of shallow grade I and 10.00% of shallow grade III). But there was no statistical significance between the two groups(P>0.05);(3) Follicle morphology of 6 months after operation: the proportion of type I follicles in the experimental group(64.52%) was higher than that of the control group(33.33%),with statistical significance(x^2 = 5.931, P=0.015).But there was no significant difference in the proportion of overall functional follicles(type I +type II) between the experimental group and the control group(x^2 =1.828, P=0.176);(4) The success rate of 6 months after operation: the total success rate was 96.77%(30 cases) in the experimental group and 86.67%(26 cases) in the control group. But there was no significant difference between the two groups(P>0.05);(5) Others: there was no significant difference in the use of antihypertensive drugs and reoperation between the two groups. CONCLUSIONS The total adjustable suture trabeculectomy group was better than the partial adjustable s
作者
陈杰
冯俊
王玮
CHEN Jie;FENG Jun;WANG Wei(Eye Hospital,China Academy of Chinese Medical Sciences,Beijing 100040,China)
出处
《中国中医眼科杂志》
2020年第8期563-566,583,共5页
China Journal of Chinese Ophthalmology
基金
中国中医科学院眼科医院院内课题(201624)。
关键词
调节缝线
小梁切除术
浅前房
低眼压
青光眼
adjustable suture
trabeculectomy
shallow anterior chamber
ocular hypotension
glaucoma
