摘要
目的深入分析中医古代疫病鼻疗方和新型冠状病毒肺炎鼻疗方(简称"新冠方")的用药特点,评估新冠方与古代疫病鼻疗方的传承关系,进而探索中医疫病鼻疗方的用药规律。方法检索《中华医典》获取5个历史时期48部古籍210条文献条目,筛选古代疫病鼻疗方132种(含燃熏方62种、挥发方63种、煎煮方7种);检索全国各地市及以上卫生主管部门官方网站和研究性文献,收集到新冠方处方20种(含挥发方12种、煎煮方8种);采用"中医传承辅助平台"软件对各类处方进行处理分析。结果①古代疫病鼻疗方共涉及178味药材,单味频次≥10次的25种,使用频次最高者为雄黄。其中燃熏方涉及103种,频次≥5次的28种,频次最高者为雄黄,药对频次最高者为"雄黄、雌黄",核心处方为"雄黄、朱砂、雌黄"。挥发方涉及142种药材,频次≥5次的30种,频次最高者亦为雄黄,药对频次最高者为"朱砂、雌黄",核心处方为"雄黄、朱砂、雌黄、鬼箭羽"。7种煎煮方涉及17种药材,频次最高者为桃枝。②20种新冠方涉及22种药材,频次≥2次的18种,使用频次最高者为艾叶。其中挥发方涉及药材18种,频次≥2次的13种,频次最高者为藿香。煎煮方涉及药材13种,频次≥2次的7种,频次最高者为艾叶。结论古代疫病鼻疗方以燃熏法和挥发法为重点,擅用矿物药,用药品种多;新冠方以挥发法和煎煮法为重点,全部采用植物药,用药品种少,对燃熏法未能有效利用。认为新冠方体现了对古代鼻疗防疫经验的传承应用,但也存在明显的研究短板,建议推进中医鼻疗防疫经验研究,为中医药参与现代传染病防控体系建设提供新的支撑。
Objective To analyze the formulation characteristics of transnasal therapy formulas for coronavirus disease 2019(COVID-19),evaluate the inheritance relationship between COVID-19 transnasal therapy formulas and ancient ones for epidemics,and further explore the formulation rules of TCM transnasal therapy formulas for epidemic diseases.Methods Through searching the Chinese Medical Classics,210 literature items of 48 ancient books in 5 historical periods were obtained,and 132 transnasal treatment formulas for ancient epidemic diseases(including 62 burning fumigation formulas,63 volatile formulas and 7 decoction formulas)were screened out.Through searching the official websites and research documents of health departments at the municipal level and above all over the country,20 formulas(including 12 volatile formulas and 8 decoction formulas)for COVID-19 were collected.The software of"Traditional Chinese Medicine Inheritance Assistance Platform"was used to process and analyze various formulas.Results(1)There were 178 kinds of medicinal materials involved in the ancient transnasal therapy for epidemic diseases,25 kinds of which had a use frequency of no less than 10 times,and Xionghuang(Realgar)was a single medicinal with the highest use frequency.Among them,103 burning fumigation formulas were involved,28 formulas of which had a use frequency more than or equal to 5 times.Xionghuang(Realgar)was the one single medicinal with the highest use frequency.Xionghuang(Realgar)and Cihuang(Orpiment)was the pair with the highest use frequency.The core formula was composed of"Xionghuang(Realgar),Zhusha(Cinnabaris)and Cihuang(Orpiment)".The volatile formulas involved 142 kinds of medicinal materials,30 of which had a use frequency more than or equal to 5 times.Xionghuang(Realgar)was still the one most frequently used.Zhusha(Cinnabaris)and Cihuang(Orpiment)was the pair used the most frequently.The core formula was composed of"Xionghuang(Realgar),Zhusha(Cinnabaris),Cihuang(Orpiment)and Guijianyu(Euonymus alatus)".There were 17 kind
作者
吴金鹏
王伟斌
岳萍
邓雪仪
陈雪吟
翁衡
于欢
王芳
唐仕欢
郭新峰
WU Jinpeng;WANG Weibin;YUE Ping;DENG Xueyi;CHEN Xueyin;WENG Heng;YU Huan;WANG Fang;TANG Shihuan;GUO Xinfeng(Chinese Medicine Engineering Research Center,Institute of Biomedical Engineering,Chinese Academy of Medical Sciences&Peking Union Medical College,Tianjin 300072,China;Library of Guangdong Provincial Hospital of Chinese Medicine,Guangzhou 5101209 China;The Second Clinical College,Guangzhou University of Chinese Medicine,Guangzhou 510120;School of Pharmacy,Jiangxi University of Traditional Chinese Medicine,Nanchang 330004,China;Key Laboratory of Ministry of Education,Jiangxi University of Traditional Chinese Medicine,Nanchang 330004,China;Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences,Beijing 100700,China;Guangdong Provincial Key Laboratory of Clinical Research on TCM Syndrome,Guangdong Provincial Hospital of Chinese Medicine,Guangzhou 510120,China)
出处
《上海中医药杂志》
2020年第9期9-15,共7页
Shanghai Journal of Traditional Chinese Medicine
基金
广东省科技厅中医证候临床研究重点实验室开放运行项目(2017B030314166)。
关键词
新型冠状病毒肺炎
新型冠状病毒
疫病
鼻疗方
芳香中药
组方规律
燃熏法
COVID-19
SARS-CoV-2
epidemic
transnasal therapy formula
aromatic traditional Chinese medicine
formulation rule
burning fumigation
