摘要
目的研究采用雷贝拉唑和雷尼替丁不同用药方案对非糜烂性胃食管反流病进行治疗的效果。方法本文观察组研究对象为2018年3月至2019年4月来我院进行治疗的34例非糜烂性胃食管反流病患者,所有患者均选择采用雷贝拉唑治疗,对照组患者为同期来我院进行治疗的另外34例非糜烂型胃食管反流病患者,所有患者均使用雷尼替丁进行治疗。对两组患者经过治疗之后的治疗总有效率、病情的复发率、并发症发生率、治疗前后的生活质量等情况进行统计和比较。结果本文观察组患者治疗以后的治疗总有效率为88.24%,其中治疗显效18例,治疗有效12例,明显高于对照组的67.65%(其中显效14例,有效9例),P <0.05;观察组患者治疗以后复发率为3.33%,出现1例复发患者,明显低于对照组的34.78%(8例),P <0.05;观察组患者治疗后并发症发生率为5.88%(2例),明显低于对照组的26.47%(9例),P <0.05;以QOL量表对两组患者治疗前后的生活质量进行评价,治疗以前两组患者相互比较,P> 0.05,无明显差异,治疗以后观察组的生活质量评分要明显高于对照组,P <0.05。结论对非糜烂性胃食管反流病患者治疗时通过雷贝拉唑进行治疗所取得的效果优于雷尼替丁,能够更好的控制患者的病症症状,提升生活质量,值得推广。
Objective To study the effects of different drug regimens of rabeprazole and ranitidine on non-erosive gastroesophageal reflux disease.Methods The research subjects of the observation group in this article were 34 patients with non-erosive gastroesophageal refl ux disease who came to our hospital for treatment from March 2018 to April 2019.Another 34 patients with non-erosive gastroesophageal refl ux disease who came to our hospital for treatment were treated with ranitidine,and the total eff ective rate,recurrence rate,and complications of the two groups of patients after treatment statistics and comparison were made on the incidence,quality of life before and after treatment.Results The total eff ective rate of the observation group after treatment in this article was 88.24%,of which 18 cases were markedly eff ective and 12 cases were eff ective,which was signifi cantly higher than 67.65%of the control group(including 14 markedly eff ective and 9 eff ective),P<0.05;observation after treatment,the recurrence rate was 3.33%,and one patient recurred,which was signifi cantly lower than 34.78%(8 cases)of the control group,P<0.05;the incidence of complications after the treatment in the observation group was 5.88%(2 cases),which was signifi cantly lower in 26.47%(9 cases)of the control group,P<0.05;the QOL scale was used to evaluate the quality of life of the two groups of patients before and after treatment.Before treatment,the two groups of patients were compared with each other,P>0.05,no signifi cant diff erence,observed after treatment the quality of life score of the group was signifi cantly higher than that of the control group,P<0.05.Conclusion The treatment eff ect of rabeprazole on non-erosive gastroesophageal refl ux patients is better than that of ranitidine.It can better control the symptoms of patients and improve the quality of life,which is worthy of promotion.
作者
孙志敏
SUN Zhimin(Jinzhou Heishan Renhe Hospital,Jinzhou 121400,China)
出处
《中国医药指南》
2020年第24期45-46,共2页
Guide of China Medicine
关键词
非糜烂性胃食管反流病
雷贝拉唑
雷尼替丁
Non-erosive gastroesophageal refl ux disease
Rabeprazole
Ranitidine
