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盐酸氨溴索联合抗生素用于慢性支气管炎治疗的效果 被引量:4

The Effect of Ambroxol Hydrochloride Combined with Antibiotics in the Treatment of Chronic Bronchitis
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摘要 目的评价联合用药(盐酸氨溴索联合抗生素)治疗慢性支气管炎的可行性以及治疗效果,以促进慢性支气管炎患者症状体征改善,进一步提高患者安全性与治疗效果。方法选择该院2018年3月—2019年5月期间收治治疗的慢性支气管炎患者,总计102例。采取随机法,进行102例慢性支气管炎患者治疗分组,即对照组、联合组。对照组51例患者采取盐酸氨溴索治疗,联合组51例患者采取盐酸氨溴索联合抗生素治疗。比较对照组与联合组慢性支气管炎患者治疗后效果、肺功能指标水平改善情况以及症状评分、症状消失时间、住院时间。结果联合组与对照组慢性支气管炎患者治疗后总有效率94.11%vs 78.43%比较,差异有统计学意义(χ~2=5.299,P=0.021)。另外,组间相关计量指标比较,差异有统计学意义(P<0.05)。结论对比盐酸氨溴索治疗,盐酸氨溴索联合抗生素治疗可以促进慢性支气管炎患者肺功能改善、缩短患者治疗与康复时间,进一步保障了治疗效果。 Objective To evaluate the feasibility and therapeutic effect of combined medication(ambroxol hydrochloride combined with antibiotics)in the treatment of chronic bronchitis,to promote the improvement of symptoms and signs in patients with chronic bronchitis,and to further improve the safety and treatment effect of patients.Methods A total of 102 patients with chronic bronchitis were treated in our hospital from March 2018 to May 2019.A randomized method was adopted to treat 102 patients with chronic bronchitis,namely control group and combined group.51 patients in the control group were treated with ambroxol hydrochloride and 51 patients in the combined group were treated with ambroxol hydrochloride combined with antibiotics.The effects of chronic bronchitis in the control group and the combined group after treatment,the improvement of lung function index levels,the symptom score,the time of symptom disappearance,and the length of hospitalization were compared.Results Compared with the control group,the total effective rate of patients with chronic bronchitis after treatment was 94.11%vs 78.43%,there was a statistically significant difference(χ~2=5.299,P=0.021).In addition,the relative measurement indexes between groups were a statistically significant difference(P<0.05).Conclusion Compared with ambroxol hydrochloride treatment,ambroxol hydrochloride combined with antibiotic treatment can promote the improvement of lung function in patients with chronic bronchitis,shorten the treatment and recovery time of patients,and further ensure the treatment effect.
作者 陈培军 CHEN Pei-jun(Department of Internal Medicine,Dahailin Forestry Bureau,Hailin,Heilongjiang Province,157125 China)
出处 《系统医学》 2020年第13期43-45,共3页 Systems Medicine
关键词 慢性支气管炎 盐酸氨溴索 抗生素 康复时间 治疗效果 Chronic bronchitis Ambroxol hydrochloride Antibiotics Rehabilitation time Treatment effect
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