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深度水解蛋白奶粉和肠外营养干预新生儿非感染性腹胀的疗效和安全性比较 被引量:2

Comparison of Efficacy and Safety of Deep Hydrolyzed Protein Milk Powder and Parenteral Nutrition for Intervention of Neonatal Non-infectious Abdominal Distension
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摘要 目的:研究对比深度水解蛋白奶粉和肠外营养干预新生儿非感染性腹胀的疗效和安全性。方法:回顾性分析2017年7月-2018年7月于笔者所在医院新生儿科确诊的86例非感染性腹胀新生儿的临床资料,其中42例喂养深度水解蛋白奶粉治疗作为处理组,另外44例禁食、采取肠外营养支持作为对照组,两组均治疗2周,治疗结束后统计两组治疗总有效率并比较,同时比较两组达全胃肠喂养时间、出生体重恢复时间、排尽胎便时间,体重增长速度和喂养不耐受发生率。结果:处理组治疗总有效率高于对照组,差异有统计学意义(P<0.05)。处理组达全胃肠喂养时间、出生体重恢复时间、排尽胎便时间均短于对照组,体重增长速度快于对照组,差异均有统计学意义(P<0.05)。处理组喂养不耐受发生率为7.14%,低于对照组的27.27%,差异有统计学意义(P<0.05)。结论:深度水解蛋白奶粉治疗非感染性腹胀新生儿效果显著,患儿恢复快,喂养不耐受发生率低,安全可靠。 Objective:To compare the efficacy and safety of deep hydrolyzed protein milk powder and parenteral nutrition in the intervention of neonatal non-infectious abdominal distension.Method:The clinical data of 86 neonates with non-infectious abdominal distension diagnosed in the neonatology department of the author’s hospital from July 2017 to July 2018 were retrospectively analyzed.Among them,42 cases were treated with deep hydrolyzed protein milk powder as the treatment group,and 44 cases were treated with fasting and parenteral nutrition support as the control group.Both groups were treated for 2 weeks,after the end of treatment,the total effective rate of treatment was calculated and compared between the two groups.Meanwhile,the time of total gastrointestinal feeding,birth weight recovery time,time of exhausted fetal stool,rate of weight gain and incidence of feeding intolerance were also compared between the two groups.Result:The total therapeutic efficiency in the treatment group was significantly higher than that in the control group,the difference was statistically significant (P<0.05).The recovery time to birth weight,the time recover to intestinal feeding and the birth weight recovery time were shorter than those in the control group,and the weight growth rate in the treatment group was faster than that in the control group,the differences were statistically significant (P<0.05).The incidence of feeding intolerance in the treatment group was 7.14%,lower than 27.27% in the control group,the difference was statistically significant (P<0.05).Conclusion:The effect of deep hydrolyzed protein milk powder on non-infectious abdominal distention neonates is remarkable,the recovery of children is fast,the incidence of feeding intolerance is low,and it is safe and reliable.
作者 王霞 冯明华 黄伟棠 杨春晖 赖春华 WANG Xia;FENG Minghua;HUANG Weitang;YANG Chunhui;LAI Chunhua(Zhongshan Bo’ai Hospital,Zhongshan 528403,China;不详)
机构地区 中山市博爱医院
出处 《中外医学研究》 2020年第22期149-151,共3页 CHINESE AND FOREIGN MEDICAL RESEARCH
关键词 深度水解蛋白奶粉 新生儿 非感染性腹胀 疗效 安全性 Deep hydrolyzed protein milk powder Newborn Non-infectious abdominal distension Curative effect Security
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