摘要
目的分析艾司西酞普兰治疗帕金森合并抑郁的可行性。方法本研究选取2017年8月~2019年6月我院帕金森合并抑郁症患者64例,随机将其分为A组32例和B组32例,B组采用西酞普兰治疗,A组采用艾司西酞普兰治疗,比较A组与B组的最终治疗效果。结果经过治疗后,两组患者的治疗有效率、抑郁相关临床指标与治疗依从性,A组治疗成效更佳,差异有统计学意义(P<0.05);不良反应发生比较,差异无统计学意义(P>0.05)。结论帕金森合并抑郁症患者应用艾司西酞普兰治疗效果更佳,能够有效改善患者的相关抑郁临床指标与运动功能,因此,值得广泛的应用与推广于现代临床医学当中。
Objective To analyze the feasibility of escitalopram in treating Parkinson's disease with depression.Methods In this study,64 patients with Parkinson's disease and depression who came to our hospital from August 2017 to June 2019 were taken as the research objects.They were randomly divided into group A(n=32)and group B(n=32),group B patients were treated with citalopram,group A patients were treated with escitalopram,and the final treatment effect was compared between groups A and B.Results After treatment,the treatment efficiency,clinical indicators related to depression,the probability of adverse reactions,and treatment compliance were compared between the two groups of patients.The treatment effect was better in group A,there were statistically significant(P<0.05).There was no significant difference in the probability of adverse reactions(P>0.05).Conclusion Escitalopram is more effective in patients with Parkinson's disease combined with depression,which can effectively improve the clinical indicators and motor function of patients'depression.Therefore,it is worthy of being widely applied and popularized in modern clinical medicine.
作者
苗玉敏
MIAO Yumin(Department of Internal Medicine,Shanghai MCC Hospital,Shanghai 200941,China)
出处
《中国医药科学》
2020年第15期94-96,共3页
China Medicine And Pharmacy
