摘要
SARS-CoV-2引起的新型冠状病毒肺炎正在全球蔓延,ACE2被认为是此病毒入侵人体的门户。高血压作为人群最常见的慢性疾病之一,众多患者使用降压药物RAAS阻滞剂,而实验提示RAAS阻滞剂可升高ACE2水平,因此,新冠肺炎高血压患者是否应继续服用RAAS阻滞剂成为国内外专家讨论的热点。本文结合近日多个高血压国际学会发表的声明,对新冠肺炎下高血压患者RAAS阻滞剂的使用进行了深入的分析和探讨。
Coronavirus disease 2019(COVID-19)caused by SARS-CoV-2 is spreading all over the word.ACE2 is considered as the target receptor to invade humans.Hypertension is one of the most common non-communicable diseases.Many hypertensive patients are treated with RAAS inhibitors,whichare reported toincrease the expression of ACE2.Hence,whether hypertensive patients should continue the therapy of RAAS inhibitors has become the concern around the world.Considering the recent statements from several authoritative organizations,in this article,we make an in-depth discussion on the use of RAAS inhibitors for hypertensive patients.
作者
陈晨
牟建军
CHEN Chen;MU Jianjun(Department of Cardiology,The First Affiliated Hospital of Xi'an Jiaotong University,Xi'an 710061,China)
出处
《西安交通大学学报（医学版）》
CAS
CSCD
北大核心
2020年第5期802-806,共5页
Journal of Xi’an Jiaotong University（Medical Sciences）
基金
国家自然科学基金资助项目(No.81870319,No.81700368)。
