摘要
目的:研究生长抑素辅助治疗粘连性肠梗阻的临床效果。方法:选取2016年1月—2018年1月我院收治的256例粘连性肠梗阻患者作为研究对象,按随机数字法分为对照组(n=128)和观察组(n=128)。对照组予以乌司他丁治疗,观察组在对照组的基础上予以生长抑素治疗。观察两组治疗总有效率、临床缓解指标、两组的血清炎性因子水平和不良反应情况。结果:观察组的总有效率为85.1%(109/128)显著高于对照组的75.8%(92/128)(P<0.05)。观察组临床缓解指标明显低于对照组(P<0.05)。两组血清降钙素原降低不明显、超敏C反应蛋白(hs-CRP)水平均显著降低(P<0.05),观察组不良反应总发生率为6.3%(8/128)低于对照组的23.4%(30/128)(P<0.05)。结论:生长抑素辅助乌司他丁治疗粘连性肠梗阻可提高临床疗效,降低炎症反应,减少不良反应,可临床推广。
Objective:To study the clinical effect of somatostatin in the treatment of adhesive ileus. Methods:From January 2016 to January2018,256 patients with adhesive ileus in our hospital were selected as the study objects,and divided into control group(n=128) and observation group(n=128) according to the random number method. The control group was treated with ulinastatin,and the observation group was treated with somatostatin on the basis of the control group. The total effective rate,clinical remission index,serum inflammatory factor level and adverse reactions of the two groups were observed. Results:The total effective rate of the observation group was 85.1%(109/128),which was significantly higher than 75.8%(92/128) of the control group(P <0.05). The clinical remission index of the observation group was significantly lower than that of the control group(P<0.05). The total incidence of adverse reactions in the observation group was 6.3%(8/128)lower than that in the control group 23.4%(30/128)(P<0.05). Conclusion:The treatment of adhesive ileus with somatostatin can improve the clinical effect,reduce the inflammatory response and adverse reactions,and can be used in clinical practice.
作者
陈志权
杨淑妙
Chen Zhiquan;Yang Shumiao(Guangdong Yingde people's Hospital,513000)
出处
《北方药学》
2020年第7期80-81,共2页
Journal of North Pharmacy
