摘要
目的 探讨生长抑素联合灌肠治疗不完全性肠梗阻患者的效果。方法 选取我院2019年9月-2020年9月收治的80例不完全性肠梗阻患者作为研究对象,按照随机数字表法分为对照组(n=40,予以灌肠治疗)和观察组(n=40,在对照组的基础上联合生长抑素),观察两组治疗效果、临床指标、血清炎症指标及免疫水平的发生情况。结果 治疗后,观察组中总体有效率为92.50%(37/40)明显高于对照组的77.50%(31/40)(P <0.05);观察组胃肠减压量低于对照组,住院时间、腹痛腹胀缓解时间、肛门排气时间短于对照组(P <0.05);两组血清炎症指标[白介素-6(IL-6)、肿瘤坏死因子α(TNF-α)、超敏C-反应蛋白(hsCRP)]均下降,观察组低于对照组(P <0.05);观察组免疫因子指标[免疫球蛋白M(IgM)、免疫球蛋白G(IgG)、免疫球蛋白A(IgA)]高于对照组(P <0.05)。结论 对于不完全性肠梗阻患者通过使用生长抑素联合灌肠治疗能够有效减轻机体的炎症反应促进免疫功能的恢复,通过降低胃肠压,缩短肛门排气时间及腹胀腹痛时间,提高治疗效果。
Objective To explore the effect of somatostatin combined with enema in the treatment of patients with incomplete intestinal obstruction. Methods A total of 80 patients with incomplete intestinal obstruction admitted to our hospital from September 2019 to September 2020 were selected as the research objects. According to the random number table method, they were divided into a control group(n =40, treated with enema) and an observation group(n =40, combined with somatostatin on the basis of conventional treatment), observe the treatment effect, clinical indicators(gastrointestinal decompression,abdominal pain and bloating relief time, anal exhaust time, hospital stay), serum inflammation indicators and The occurrence of immune levels. Results After treatment, the overall effective rate of 92.50% in the observation group was significantly higher than 77.50% in the control group(P <0.05);gastrointestinal decompression in the observation group was lower than that in the control group, hospitalization time,abdominal pain relief time, anal exhaust The time was shorter than that of the control group(P <0.05);the serum inflammatory indexes [interleukin-6(IL-6), tumor necrosis factor α(TNF-α), high-sensitivity C-reactive protein(hs-CRP)] decreased in the two groups, The observation group is lower than the control group(P <0.05);The immune factor indexes of the observation group [immunoglobulin M(IgM),immunoglobulin G(IgG), immunoglobulin A(IgA)] were higher than those of the control group(P <0.05).Conclusion For patients with incomplete intestinal obstruction, the use of somatostatin combined with enema treatment can reduce gastrointestinal pressure, shorten the time of anal exhaust and abdominal distension and abdominal pain, effectively alleviate the inflammation, promote the recovery of immune function, and improve the therapeutic effect.
作者
曹子芬
刘如锋
邓小雅
CAO Zifen;LIU Rufeng;DENG Xiaoya(Lianjiang People's Hospital,Lianjiang,Guangdong 524400)
出处
《智慧健康》
2022年第11期107-110,共4页
Smart Healthcare
关键词
生长抑素
灌肠
不完全性肠梗阻
炎症因子
Somatostatin
Enema
Incomplete intestinal obstruction
Inflammatory factor
