摘要
目的分析医院骨科患者感染肺炎克雷伯菌的分布及其耐药情况,以指导临床合理使用抗菌药物。方法通过细菌分离培养和药敏试验方法,对某医院骨科患者送检病原学标本进行检测和分析。结果共检出肺炎克雷伯菌229株,检出率有逐年增加趋势;主要分离自痰液和创面分泌物。产β-内酰胺酶菌株占37.99%。各年龄段检出产酶菌株差异有统计学意义(χ^2=15.732,P<0.05)。药敏结果显示,肺炎克雷伯菌对所试验的抗菌药物尚有一定敏感性,未检测出对碳青霉烯类耐药的菌株。结论骨科住院患者感染肺炎克雷伯菌产酶菌株的耐药性高,需要根据药物敏感试验合理选用抗生素,减少耐药率的发生。
Objective To analyze the distribution and drug resistance of Klebsiella pneumoniae infection in orthopedic patients in hospital,so as to guide the rational use of antimicrobial drugs.Methods To detect and analyze the etiology specimens of orthopedic patients in a hospital by bacterial isolation,culture and drug sensitivity test.Results A total of 229 Klebsiella pneumoniae strains were detected,and the detection rate increased year by year.The strains were mainly isolated from sputum and wound secretions.β-lactinase strain accounted for 37.99%.The difference of enzyme producing strains detected in all age groups was statistically significant(χ^2=15.732,P<0.05).The drug sensitivity results showed that Klebsiella pneumoniae was still sensitive to the antimicrobial drugs tested and no strains resistant to carbene were detected.Conclusion In Klebsiella pneumoniae infection in orthopaedic inpatients,the resistance of enzyme producing strain is high,so antibiotics should be selected reasonably according to drug sensitivity test to reduce the incidence of drug resistance.
作者
王丽丽
WANG Li-li(Clinical Laboratory,the Sixth Hospital of Ningbo,Ningbo,Zhengjiang 315000,China)
出处
《中国卫生检验杂志》
CAS
2020年第14期1703-1706,共4页
Chinese Journal of Health Laboratory Technology
关键词
骨科
肺炎克雷伯菌
抗菌药物
耐药性
Orthopaedics
Klebsiella pneumoniae
Antimicrobial drugs
Drug resistance
