摘要
目的对精细化管理与集束化清洁消毒模式对新生儿重症监护室(NICU)医院感染控制效果进行分析,并探讨两种方法的耐药菌感染、定植状况的差异。方法回顾性分析2012年1月-2015年8月新疆石河子大学医学院第一附属医院采用集束化清洁消毒模式干预的患者390例设为集束化组及2015年9月-2018年12月采用精细化管理模式干预的患者364例设为精细化组;分析两组患者医院感染发生率及感染部位,统计两组物体表面清除率及消毒液配置依从性,并分析两组多药耐药菌感染及定植情况。结果精细化组患者NICU医院感染率为2.47%(9/364)低于集束化组8.46%(33/390)(P=0.018),两组患者感染均以呼吸道感染为主;集束化组物体表面清除率及消毒液配置依从性分别为87.40%(437/500)、83.80%(419/500)均低于精细化组物体表面清除率及消毒液配置依从性分别为98.20%(491/500)、97.80%(489/500)(P<0.05);集束化组多药耐药菌定植率为22.56%(88/390)高于精细化组定植率5.49%(20/364)(P=0.019);集束化组及精细化组患者多药耐药菌感染差异有统计学意义(P<0.05)。结论相较于集束化清洁消毒模式,采用精细化管理干预后可显著控制NICU医院感染,可有效降低耐药菌定植及感染率。
OBJECTIVE To analyze the effects of fine management and cluster cleaning and disinfection model on nosocomial infection control in neonatal intensive care unit(NICU), and to explore the differences of drug-resistant bacterial infection and colonization status between the two methods. METHODS 390 patients of clustering group who underwent cluster cleaning and disinfection intervention in the first affiliated hospital of the medical college of Shihezi university of Xinjiang from Jan. 2012 to Aug. 2015 and 364 patients of meticulous group who underwent meticulous management intervention from Sep. 2015 to Dec. 2018 were retrospectively analyzed.The incidence of nosocomial infection and infection sites of the two groups of patients were analyzed, and the surface clearance rate of the two groups and the compliance of disinfectant configuration were counted, and the infection and colonization of multi-drug resistant bacteria in the two groups were analyzed. RESULTS The nosocomial infection rate of NICU in themeticulous group was 2.47%(9/364), significantly lower than that in the clustering group(8.46%, 33/390)(P=0.018), and the respiratory tract infection was the main infection in both groups. The surface clearance rate and disinfection solution configuration compliance in the clustering group were 87.40%(437/500) and 83.80%(419/500), respectively, significantly lower than those in the meticulous group(98.20%(491/500) and 97.80%(489/500), respectively)(P<0.05). The colonization rate of multidrug-resistant bacteria in the clustering group was 22.56%(88/390), significantly higher than that in the meticulous group(5.49%, 20/364)(P=0.019). There was a significant difference in the infection of multidrug-resistant bacteria infection between the clustering group and the meticulous group(P<0.05). CONCLUSION Compared with cluster cleaning and disinfection mode, meticulous management intervention can significantly control nosocomial infection in NICU, and effectively reduce the colonization and infection rate of drug-resistant b
作者
张璐
彭金玲
李红
朱冬梅
ZHANG Lu;PENG Jin-ling;LI Hong;ZHU Dong-mei(The First Affiliated Hospital of Medical College of Shihezi University,Shihezi,Xinjiang 832000,China)
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2020年第12期1910-1914,共5页
Chinese Journal of Nosocomiology
基金
新疆维吾尔自治区自然科学基金资助项目(2013211B50)。
关键词
精细化管理
集束化清洁消毒模式
新生儿重症监护室
医院感染
耐药菌感染
定植状况
Fine management
Cluster cleaning and disinfection mode
NICU
Hospital infection
Drug-resistant bacterial infection
Colonization status
