摘要
目的探讨帕金森病患者合并抑郁障碍与睡眠障碍的相关性.方法将60例帕金森病患者按照汉密顿抑郁量表17项版本评分结果 分为合并抑郁组26例与非抑郁组34例.采用匹兹堡睡眠质量指数量表对两组睡眠质量进行评估,分析合并抑郁障碍与睡眠障碍的相关性.结果 合并抑郁组汉密顿抑郁量表17项版本总分及焦虑/躯体症状、体质量减轻、昼夜节律变化、阻滞症状、睡眠障碍因子评分均显著高于非抑郁组(P<0.01).合并抑郁组匹兹堡睡眠质量指数量表总分及各因子评分均显著高于非抑郁组(P<0.05或0.01).帕金森病合并抑郁障碍患者汉密顿抑郁量表17项版本评分与匹兹堡睡眠质量指数量表评分呈显著正相关(P<0.05).结论抑郁障碍是导致帕金森病患者睡眠障碍的一个重要因素,且抑郁障碍程度越重,睡眠障碍越明显.
Objective To explore the correlation between depression and sleep disorders in patients with Parkinson's disease.Methods 60 patients with Parkinsons disease were divided into a combined depression group and a non-depression group according to the HAMD-17 score.PSQI was used to evaluate the sleep quality of the two groups,and the correlation between combined depression and sleep disorders was analyzed.Results The total score of HAMD-17,anxiety/somatic symptoms,weight loss,circadian rhythm changes,block symptorrivS,and sleep disturbance factor scores in the combined depression group were significantly higher than those in the non-depression group(P<0.01).The PSQI total score and scores of all factors in the combined depression group were significantly higher than those in the non-depression group(P<0.05 or 0.01).The HAMD-17 score and PSQI score of patients with Parkinsons disease and depression were significantly positively correlated(P<0.05).Conclusions Depression disorder is an important factor leading to sleep disorders in patients with Parkinsons disease,and the more severe the degree of depression,the more obvious the sleep disorder.
作者
赵松耀
窦海玲
李世泽
Zhao Songyao;Dou Hailing;Li Shize(Zhengzhou Central Hospital Affiliated to Zhengzhou University,Zhengzhou 450000,Henan China)
出处
《临床心身疾病杂志》
CAS
2020年第4期142-144,151,共4页
Journal of Clinical Psychosomatic Diseases
