摘要
目的探讨生活方式干预对农村2型糖尿病(T2DM)患者各项代谢指标的影响。方法随机选取山东省蓬莱市潮水镇10个自然村,对50岁以上村民进行健康筛查,以自然村为小组,每组随机抽取T2DM患者12例(共120例)作为研究对象。对所有研究对象进行生活化生活方式干预,干预3个月,比较干预前后患者腰围、血压、体质指数(BMI)、运动功能、体成分、空腹血糖、糖化血红蛋白(HbA1c)等指标的差异。相关数据分析采用配对t检验。结果108例研究对象完成实验。生活方式干预后,研究对象的腰围、BMI、空腹血糖、HbA1c等指标均明显下降,差异有显著性意义(t=1.84~10.02,均P<0.01),干预后的运动功能和体成分各项指标(下肢肌肉分布系数、脂肪分布、下肢神经及肌体反应速度等)较干预前均改善,差异有显著性意义(t=-10.64~9.56,均P<0.01)。结论生活化生活方式干预,可显著改善农村T2DM患者腰围、BMI、HbA1c、体成分、运动功能等代谢指标。
Objective To explore the effect of lifestyle intervention on metabolic indexes in rural patients with type 2 diabetes mellitus.Method Ten natural villages in Chaoshui Town,Penglai City,Shandong Province were randomly selected to screen the villagers over 50 years old.With the natural village as a group,12 T2DM patients(a total of 120)were randomly selected from each group as the object of study.All the subjects were given life style intervention,and the differences of waist circumference,blood pressure,body mass index(BMI),motor function,body composition,fasting blood glucose and glycosylated hemoglobin A1c(HbA1c)were compared before and 3 months after intervention.Paired t-test was used to analyze the related data.Result A total of 108 subjects completed the experiment.After lifestyle intervention,the waist circumference,BMI,fasting blood glucose and HbA1c decreased significantly(t=1.84 to 10.02,all P<0.01).The indexes of motor function and body composition(lower limb muscle distribution coefficient,fat distribution,lower limb nerve and body reaction speed,etc)after intervention were significantly improved as compared with those before intervention(t=-10.64 to 9.56,P<0.01).Conclusion Lifestyle intervention can significantly improve the metabolic indexes of rural patients with type 2 diabetes,such as waist circumference,BMI,HbA1c,body composition,exercise function and so on.
作者
王波
赵娟
姜海萍
李珊珊
牟肖莉
Wang Bo;Zhao Juan;Jiang Haiping;Li Shanshan;Mou Xiaoli(Department of General Medicine,Yantai Mountain Hospital,Yantai City,Yantai 264000,China)
出处
《中华糖尿病杂志》
CAS
CSCD
北大核心
2020年第7期509-512,共4页
CHINESE JOURNAL OF DIABETES MELLITUS
关键词
糖尿病
2型
农村
生活方式干预
代谢
Diabetes mellitus,type 2
Country
Lifestyle intervention
Metabolism
