摘要
睡眠对于人类的一生来说,是必不可少的组成部位,人生有三分之一的时间处于睡眠状态,许多疾病也跟睡眠有关。但是睡眠-觉醒到底是如何控制的,至今尚不明确。但可以肯定的是睡眠-觉醒系统是由多种神经肽递质参与的,其中可分为促睡眠类和促觉醒类。二者共同合作,来维持睡眠-觉醒系统。目前发现觉醒在阻塞性睡眠呼吸暂停(OSA)发病及预后过程中的作用越来越受到重视,而OSA相关觉醒的具体产生机制尚不明确。本综述重点概括了可能参与OSA相关觉醒的神经递质。
Sleep is an indispensable part of human life.One third of human life is spent sleeping.Many diseases are also related to sleep.But how sleep-arousal is controlled remains unclear.But it is certain that the sleep-arousal system is participated by a variety of neuropeptide transmitters,which can be divided into sleep-promoting and arousal-promoting categories.They work together to maintain the sleep-arousal system.It has been found that the role of arousal in the pathogenesis and prognosis of OSA has been paid more and more attention,but the specific mechanism of OSA-related arousal is still unclear.This review focuses on the possible neurotransmitters involved in OSA-related arousal.
作者
卢静成
杨立新
赵花
周宁
LU Jingcheng;YANG Lixin;ZHAO Hua;ZHOU Ning(Bengbu Medical College,Bengbu 233000,China;Huainan First People′s Hospital,Huainan 232000,China)
出处
《世界睡眠医学杂志》
2020年第6期1115-1116,共2页
World Journal of Sleep Medicine
