摘要
目的:观察膈下逐瘀汤加减方联合宫腔镜下输卵管通液术治疗输卵管阻塞性不孕症的临床疗效。方法:将40例确诊为气滞血瘀型输卵管阻塞性不孕症患者,随机分为观察组和对照组,每组20例。两组患者均于月经干净3~7 d行宫腔镜下输卵管通液术,观察组同时于月经干净第3天开始口服中药,疗程结束后,比较分析两组患者临床疗效。结果:治疗后,与对照组相比,观察组中医证候总积分下降程度更为明显(P<0.05);中医证候疗效总有效率达(19/20)95%,有显著性差异(P<0.05);观察组的输卵管通畅率显著升高,阻塞率显著下降,总复通数显著升高,差异有统计学意义(P<0.05);观察组患者妊娠率显著升高,差异有统计学意义(P<0.05)。结论:膈下逐瘀汤加减能够显著改善输卵管不孕患者中医证候,联合宫腔镜下输卵管通液术更有利于提高输卵管复通率及受孕率。
Objective: To observe the clinical effect of modified Gexia Zhuyu Decoction combined with hysteroscopic hydrotubation in the treatment of tubal obstructive infertility. Methods: 40 cases, diagnosed as bilateral oviduct obstructive infertility with qi stagnation and blood stasis, were randomly divided into the observation group and the control group, with 20 cases in each group. Both groups received hysteroscopic hydrotubation 3-7 days after menstruation, and the observation group was treated with TCM medication on the 3 rd day after menstruation. The clinical efficacy was compared between the two groups. Results: The total score of TCM syndromes decreased significantly in the observation group compared to that in the control group after the treatment(P<0.05). The total effective rate of TCM syndromes was 95%(19/20) in the observation group, which was significantly higher than that in the control group(P<0.05). In the observation group, the patency rate of fallopian tube increased significantly, the blocking rate decreased significantly, and the total improved cases increased significantly(P<0.05). The pregnancy rate in the observation group was significantly higher than that in the control group(P<0.05). Conclusion: Modified Gexia Zhuyu Decoction can significantly improve the TCM syndrome of tubal infertility patients, combined with hysteroscopic hydrotubation is more conducive to improve tubal recanalization rate and pregnancy rate.
作者
胡喜姣
李红梅
王晓滨
杨东霞
李兰
孙萌
赵晶晶
刘丽
HU Xijiao;LI Hongmei;WANG Xiaobin;YANG Dongxia;LI Lan;SUN Meng;ZHAO Jingjing;LIU Li(The Second Affiliated Hospital of Heilongjiang University of Chinese Medicine,Harbin 150001,China;The First Affiliated Hospital of Heilongjiang University of Chinese Medicine,Harbin 150040,China)
出处
《中医药学报》
CAS
2020年第7期54-57,共4页
Acta Chinese Medicine and Pharmacology
基金
黑龙江省中医药管理局科研项目(ZHY18-087)
黑龙江中医药大学附属第二医院科研项目(YQ-201703)。
关键词
膈下逐瘀汤
不孕症
气滞血瘀
宫腔镜
输卵管
Gexia Zhuyu Decoction
Infertility
Qi stagnation and blood stasis
Hysteroscopy
Fallopian tubes
