摘要
近年来,儿童哮喘患病率在全球范围内呈上升趋势。甲醛作为一种常见的室内污染物,对哮喘的作用愈发引起关注,但是目前研究结果并未统一。有研究表明哮喘患儿居住的室内环境中,甲醛浓度明显高于健康儿童,也有文献报道甲醛并不是哮喘发生的独立危险因素,确切结果尚需进一步的研究。该文从气道炎症、获得性过敏体质、酶学等角度探讨了甲醛对哮喘可能的作用机制,为哮喘的防治工作提供了新思路。
In recent years,the prevalence of childhood asthma has been increasing globally.As a common indoor pollutant,formaldehyde is involved in the pathogenesis of asthma,which has drawn increasing attention.However,the results of the current research have not been unified.Some studies have shown that asthma children live in indoor environments where the concentration of formaldehyde is significantly higher than that of healthy children.There are also reports showing that formaldehyde is not an independent risk factor for asthma.The exact results need to be further studied with a larger sample size.In addition,the article concludes the possible mechanism of formaldehyde on asthma from the perspectives of airway inflammation,acquired allergies,and enzymology,providing new ideas for the prevention and treatment of asthma.
作者
任洁
李娈娈(综述)
鲍一笑(审校)
Ren Jie;Li Luanluan;Bao Yixiao(Department of Pediatrics,Shanghai Children′s Medical Center,Shanghai Jiao Tong University School of Medicine,Shanghai 200127,China)
出处
《国际儿科学杂志》
2020年第6期380-383,共4页
International Journal of Pediatrics
基金
国家自然科学基金(81870024)。
关键词
儿童
甲醛
哮喘
Children
Formaldehyde
Asthma
