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2012~2019年辽宁某医院254例中药不良反应报告分析 被引量:4

Analysis of 254 cases of adverse reaction reports of traditional Chinese medicine in a hospital of Liaoning from 2012 to 2019
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摘要 目的分析辽宁某医院中药不良反应的发生情况及中药发生不良反应的特点,旨在帮助医务人员了解中药不良反应发生的一般规律,保证患者临床用药更合理、更安全、更有效。方法采用回顾性研究方法选取2012~2019年辽宁某医院上报国家药品不良反应监测中心的254例中药药品不良反应报告,按发生年度、患者年龄、性别、药品剂型、给药途径、涉及系统及临床症状等进行分析。结果中药不良反应在60岁及以上患者中多发,主要以中药注射剂为主(77.95%),中药不良反应报告中前5位均为为中药注射剂,排名第一的药品是注射用血栓通(冻干),以皮肤及其附件损害为最常见的中药不良反应。结论加强中药不良反应的监测和报告工作,确保临床合理用药。 Objective To help medical staff understand the general rule of occurrence of adverse reactions of traditional Chinese medicine by analyzing the occurrence of adverse reactions of traditional Chinese medicine and the characteristics of adverse reactions of traditional Chinese medicine in a hospital in Liaoning,so as to ensure that patients'clinical medication is more reasonable,safer and more effective.Methods 254 cases of adverse drug reaction reports of traditional Chinese medicines reported to the National Center for Adverse Drug Reactions in a hospital in Liaoning from 2012 to 2019 were selected by using retrospective research method.According to the year of occurrence,patient age,sex,drug dosage form,route of administration,related systems and clinical symptoms were analyzed.Results The adverse reactions of traditional Chinese medicine were frequent among patients aged 60 years and above,mainly with traditional Chinese medicine injections(77.95%).The top 5 reports of adverse reaction of traditional Chinese medicines were all traditional Chinese medicine injections,and the first ranked drug was thrombosis for injection(frozen dry).The most common adverse reactions of traditional Chinese medicine were skin and accessory damage.Conclusion The monitoring and reporting of adverse reactions of traditional Chinese medicine should be strengthened,to ensure the rational use of drugs in the clinic.
作者 马婷 MA Ting(Department of Medicinal Materials,Chaoyang Central Hospital,Chaoyang122000,China)
出处 《中国现代医生》 2020年第16期111-114,共4页 China Modern Doctor
关键词 中药 不良反应 合理用药 辽宁 Chinese medicine Adverse reactions Rational use of drugs Liaoning
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