摘要
目的分析新型冠状病毒肺炎(简称新冠肺炎)患者的流行病学及临床特征,为临床诊疗提供参考。方法回顾性分析福建医科大学附属泉州第一医院2020年1月23日至2月9日收治的41例新冠肺炎确诊患者的临床资料,观察其流行病学、临床表现、实验室检查和影像学检查特点。结果共纳入41例新冠肺炎确诊患者,其中男性19例,女性22例;年龄4~77岁,中位年龄38.00(31.00,50.75)岁;32例(78.05%)为输入性病例,9例(21.95%)在本地接触输入性确诊病例,为2代感染病例。临床分型以轻型和普通型为主,其中轻型9例(21.95%)、普通型28例(68.29%)、重型3例(7.32%)、危重型1例(2.44%)。所有患者平均潜伏期(6.05±3.84)d,最长达19 d;主要表现为发热〔80.49%(33/41)〕、咳嗽〔46.34%(19/41)〕、咳痰〔31.71%(13/41)〕,以低热为主。胸部CT显示,32例存在肺部异常病灶,其中25例(78.13%)累及双肺,主要表现为磨玻璃影〔81.25%(26/32)〕及斑片、实变影〔71.88%(23/32)〕。入院时白细胞计数(WBC)降低7例(17.07%)、升高1例(2.44%),淋巴细胞计数(LYM)减少13例(31.71%),C-反应蛋白(CRP)升高15例(36.59%),降钙素原(PCT)均正常。T淋巴细胞亚群中,CD4+T淋巴细胞计数减少15例(36.59%),CD8+T淋巴细胞计数减少12例(29.27%)。结论泉州地区新冠肺炎以输入性病例为主,发病人群以中青年为主,主要表现为发热、咳嗽、咳痰,出现呼吸困难症状较少;临床分型以轻型和普通型为主,胸部CT主要表现为双肺多发磨玻璃影或实变影,以双下肺、外带为主。
Objective To analyze the epidemiological and clinical characteristics of coronavirus disease 2019(COVID-19)patients.Methods The clinical data of 41 patients with COVID-19 admitted in Quanzhou First Hospital Affiliated to Fujian Medical University from January 23 to February 9,2020 were retrospectively analyzed.Features of epidemiology,clinical symptoms,laboratory inspections and imaging inspections were observed.Results Among the 41 patients included in this study,19 cases were male and 22 cases were female,aged 4-77 years old,with a median age of 38.00(31.00-50.75)years old.There were 32(78.05%)imported cases,and 9 cases(21.95%)were second-generation infections.The clinical classifications were mainly mild and common type,among which 9 cases were mild type(21.95%),28 cases were common type(68.29%),3 cases were severe type(7.32%),and 1 case was critical type(2.44%).All the cases had an average incubation period of(6.05±3.84)days,the longset up to 19 days.The main manifestations were fever[80.49%(33/41)],cough[46.34%(19/41)],expectoration[31.71%(13/41)],mainly low grade fever.Chest CT showed that 32 cases had visible lung shadow,of which 25 cases(78.13%)were involved in both lungs,mainly with ground glass shadow[81.25%(26/32)]and patch consolidation shadow[71.88%(23/32)].At admission,the white blood cell count(WBC)decreased in 7 cases(17.07%)and increased in 1 case(2.44%),and lymphocytes count(LYM)decreased in 13 cases(31.71%),C-reactive protein(CRP)increased in 15 cases(36.59%),and procalcitonin(PCT)was in normal in all,CD4+T lymphocytes decreased in 15 cases(36.59%),and CD8+T lymphocytes decreased in 12 cases(29.27%).Conclusions The COVID-19 cases in Quanzhou region are mainly imported cases,the majority of patients were young and middle-aged.The main manifestations are fever,cough,and expectoration,while dyspnea symptoms are less.The clinical classifications are mainly in mild and common type.Chest CT mainly shows ground-glass shadows or solid shadows of multiple lungs,mainly of lower lungs and external lungs.
作者
吴燕玲
庄锡彬
黄鸿波
林艺坚
Wu Yanling;Zhuang Xibin;Huang Hongbo;Lin Yijian(Department of Respiratory and Critical Medicine,Quanzhou First Hospital Affiliated to Fujian Medical University,Quanzhou 362000,Fujian,China)
出处
《中国中西医结合急救杂志》
CAS
CSCD
北大核心
2020年第4期390-393,共4页
Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care
关键词
新型冠状病毒肺炎
流行病学
临床特征
分析
Coronavirus disease 2019
Epidemiology
Clinical characteristics
Analysis
