摘要
目的探讨卡前列素氨丁三醇联合垂体后叶素及催产素对剖宫产后出血的防治作用。方法选取2016年3月至2018年6月佛山市禅城中心医院诊治的162例具有产科剖宫产指征并存在产后出血倾向的产妇作为研究对象。随机分为观察组(n=81)和对照组(n=81),观察组产妇采用卡前列素氨丁三醇联合垂体后叶素治疗,对照组产妇采用卡前列素氨丁三醇联合催产素治疗。比较两组术后的疗效、出血量、出血量、血红蛋白水平及不良反应。结果观察组产妇胎儿娩出后2h和24h的出血量均显著低于对照组产妇,差异具有统计学意义(P<0.05)。观察组产妇的产后出血率(16.05%)显著低于对照组产妇(29.63%),差异具有统计学意义(P<0.05)。观察组产妇的治疗有效率(95.06%)显著高于对照组产妇(90.12%),差异具有统计学意义(P<0.05)。观察组产妇术后24h的血红蛋白水平显著高于对照组产妇,差异具有统计学意义(P<0.05)。两组产妇不良反应发生率比较,差异无统计学意义(P>0.05)。结论卡前列素氨丁三醇联合垂体后叶素防治剖宫产后出血的效果显著,可有效降低产后出血量和出血率,防止血红蛋白水平降低,并且无严重不良反应。
Objective To investigate the preventive and therapeutic effects of Romethamine combined with pituitrin and oxytocin on postpartum hemorrhage after cesarean section.Methods From March 2016 to June 2018,162 pregnant women with indications of obstetric cesarean section and postpartum hemorrhagic tendencies in Foshan Chancheng Central Hospital were selected as subjects.They were randomly divided into observation group(n=81)and control group(n=81).The observation group was treated with romethamine combined with pituitrin,and the control group was treated with romethamine combined with oxytocin.The efficacy,bleeding volume,blood loss,hemoglobin level and adverse reactions were compared between the two groups.Results The amount of bleeding at 2 h and 24 h after delivery in the observation group was significantly lower than that in the control group(P<0.05).The postpartum hemorrhage rate of the observation group(16.05%)was significantly lower than that of the control group(29.63%).The effective rate of treatment in the observation group(95.06%)was significantly higher than that in the control group(90.12%).The hemoglobin level at 24 h after treatment in the observation group was significantly higher than that of the control group(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusions Romethamine combined with pituitrin has significant effect on prevention and treatment of postpartum hemorrhage,which can effectively reduce postpartum hemorrhage rate and bleeding volume,prevent hemoglobin level from decreasing,and with no serious adverse reactions.
作者
吴志丽
黄秀英
关珊珊
劳力
杨仪心
WU Zhili;HUANG Xiuying;GUAN Shanshan;LAO Li;YANG Yixin(Department of Obstetrics and Gynecology,Foshan Chancheng Central Hospital,Foshan 528042,Guangdong,China)
出处
《中国性科学》
2020年第7期89-92,共4页
Chinese Journal of Human Sexuality
基金
佛山市卫生和计生局课题(20170176
20170168)。
