摘要
目的讨论布托啡诺复合地塞米松预防剖宫产术中卡前列素不良反应的效果。方法抽取2017年1月至2019年1月于洛阳市妇幼保健院行剖宫产分娩的产妇120例,应用随机数字表法将患者分为对照组与观察组,每组60例。对照组在子宫体注射卡前列素氨丁三醇的同时给予产妇布托啡诺静脉注射处理,观察组在对照组治疗基础上给予产妇布托啡诺复合地塞米松静脉注射处理。观察两组患者术中不良反应发生情况;观察两组产妇手术前、子宫体注药10 min后、手术后等时间节点处的镇静评分。记录对比两组产妇手术前、子宫体注药40 min后、手术后等时间节点处的血流动力学指标水平。结果与对照组比较,观察组胸闷憋气、呕吐、面部潮红、恶心、高血压、寒战、心动过速等不良反应的发生率降低(P<0.05)。手术前,两组产妇镇静评分比较,差异未见统计学意义(P>0.05);子宫体注药10 min后,对照组镇静评分呈现显著下降趋势,而观察组镇静评分呈现明显上升趋势,两组镇静评分比较,差异有统计学意义(P<0.05)。手术前,两组产妇心率、平均动脉压、呼吸频率等血流动力学指标比较差异未见统计学意义(P>0.05);子宫体注药40 min后,两组产妇的心率、平均动脉压、呼吸频率均明显升高,但观察组增高幅度低于对照组(P<0.05)。结论应用布托啡诺复合地塞米松预防剖宫产术中卡前列素不良反应的临床效果理想,能有效缓解产妇的不适感,降低不良反应的发生率。
Objective To discuss the effect of butorphanol combined with dexamethasone in preventing adverse reactions of carprost in cesarean section.MethodsA total of 120 women who underwent cesarean delivery in Luoyang Maternal and Child Health Hospital from January 2017 to January 2019 were screened. The patients were divided into reference group and observation group by random number table method, 60 cases in each group. The reference group was given intravenous injection of buprenorphine in uterine body, the observation group was treated with butorphanol and dexamethasone on the basis of the control group. The incidences of adverse reactions in the two groups were compared. The sedation scores of the two groups of women were observed and compared before operation, 10 minutes after uterine body injection, and after completion of operation. The hemodynamic index levels of the two groups of women were recorded before operation, 40 minutes after uterine body injection, and after operation.Results Compared with reference group, the incidence of adverse reactions such as vomiting, nausea, chest tightness, facial flushing, hypertension, chills and tachycardia in the observation group showed a significant downward trend(P<0.05). Before operation, there was no significant difference in the Ramsay sedation scores between the two groups (P>0.05). Ten minutes after uterine body injection, the sedation score of control group showed a significant downward trend, while that of observation group showed a significant upward trend (P<0.05). Before operation, there were no significant differences in the hemodynamic parameters such as heart rate, respiratory rate, and mean arterial pressure between the two groups (P>0.05). Forty minutes after uterine body injection, the heart rate, mean arterial pressure and respiratory rate of the two groups were significantly increased, but the increasing range of observation group was lower than that of control group (P<0.05).Conclusions The clinical effect of budesonol combined with dexamethasone in p
作者
刘慧锦
杨丹丹
侯春洁
Liu Huijin;Yang Dandan;Hou Chunjie(Department of Anesthesiology,Luoyang Maternal and Child Health Hospital,Luoyang 471000,China;Department of Anesthesiology,the Third Affiliated Hospital of Henan University of Science and Technology,Luoyang 471000,China)
出处
《中国实用医刊》
2020年第4期81-84,共4页
Chinese Journal of Practical Medicine
