摘要
目的:探讨硝酸酯类药物治疗心血管疾病的疗效研究.方法:随机将2018年6月-2019年6月在东莞市虎门医院心内科治疗的116例心血管疾病(均为冠状动脉粥样硬化性心脏病、心肌梗死)患者进行分组,对照组采用常规药物治疗,在此基础上观察组使用硝酸酯类药物治疗,比较两组患者的临床疗效、心绞痛改善情况和不良反应.结果:观察组治疗有效率为94.83%(55/58),明显高于对照组的74.14%(43/58)(P<0.05);观察组治疗后心绞痛发作频率、每次持续时间均明显少于对照组(P<0.05);观察组面部潮红、头痛、恶心呕吐、低血压、皮肤过敏等不良反应发生率与对照组相比无明显差异(P>0.05).结论:硝酸酯类药物治疗心血管疾病的疗效显著,能有效扩张血管,缓解心绞痛,且安全性较高,具有积极的临床意义.
Objective:To study the effect of nitrates on cardiovascular diseases.Methods:116 patients with cardiovascular diseases(coronary heart disease and myocardial infarction)treated in the department of cardiology of Department of Cardiology Humen Hospital,Dongguan from June 2018 to June 2019 were randomly divided into groups.The control group was treated with conventional drugs,and the observation group was treated with nitrates.The clinical efficacy,improvement of angina pectoris and adverse reactions of the two groups were compared.Results:The effective rate of treatment in the observation group was 94.83%(55/58),which was significantly higher than that in the control group 74.14%(43/58)(P<0.05).The frequency and duration of angina attack in the observation group were significantly lower than those in the control group(P<0.05).The incidence of facial flushing,headache,nausea and vomiting,hypotension and skin allergy in the observation group was not significantly different from that in the control group(P>0.05).Conclusion:Nitrates are effective in the treatment of cardiovascular diseases.They can effectively dilate blood vessels and relieve angina pectoris.Moreover,they are safe and have positive clinical significance.
作者
洪楚亮
熊美
Hong Chuliang;Xiong Mei
出处
《中医临床研究》
2020年第15期56-57,共2页
Clinical Journal Of Chinese Medicine
关键词
心血管疾病
硝酸酯类药物
疗效
Cardiovascular disease
Nitrates
The curative effect
