摘要
目的 探讨参苓白术散辅助治疗初治肺结核的临床效果.方法 选择2018年1~12月肺结核患者100例为研究对象,随机分为观察组与对照组,各50例.两组均给予2SHRZ/4HR治疗,观察组在此基础上给予参苓白术散辅助治疗.比较两组治疗后中医证候积分,中医证候疗效、病灶变化,痰菌转阴率,红细胞沉降率及不良反应.结果 (1)治疗后,两组ESR较治疗前均显著下降,差异有统计学意义(P<0.05);治疗后,观察组ESR显著低于对照组,差异有统计学意义(P<0.05).(2)治疗后,两组中医证候积分较治疗前均显著改善,差异有统计学意义(P<0.05);治疗后,观察组中医证候积分显著低于对照组,差异有统计学意义(P<0.05).(3)秩和检验显示,观察组中医证候疗效显著优于对照组,差异有统计学意义(P<0.05).(4)秩和检验显示观察组治疗后病灶显著吸收率显著高于对照组,差异有统计学意义(P<0.05).(5)观察组治疗后45例痰菌转阴,转阴率为90.0%;对照组36例痰菌转阴,转阴率为72.0%.两组比较差异有统计学意义(P<0.05).(6)观察组不良反应严重程度显著低于对照组,差异有统计学意义(P<0.05).结论 参苓白术散辅助治疗初治肺结核,可显著改善症状,提高痰菌转阴率,能有效缓解患者不良反应情况.
Objective To explore the clinical effect of Shenling Baizhu powder in adjuvant treatment of newly treated tuberculosis.Methods A total of 100 patients with tuberculosis from January to December 2018 were selected as the research subjects and randomLy divided into an observation group and a control group,with 50 cases in each group.Both groups were treated with 2SHRZ/4HR,and the observation group was given adjuvant treatment with Shenling Baizhu powder on the basis of this.TCM syndrome scores,efficacy of TCM syndromes,lesion changes,sputum negative conversion ratio,erythrocyte sedimentation rate and adverse reaitions were compared between the two groups after treatment.Results(1)After treatment,the ESR in both groups was significantly lower than that before treatment,and the difference was statistically significant(P<0.05);after treatment,the ESR in the observation group was significantly lower than that in the control group,and the difference was statistically significant(P<0.05).(2)After treatment,the TCM syndrome scores of the two groups were significantly improved compared with those before treatment,and the differences were statistically significant(P<0.05);after treatment,the TCM syndrome score of the observation group was significantly lower than that of the control group,and the difference was statistically significant(P<0.05).(3)Rank sum test showed that the efficacy of TCM syndromes in the observation group was significantly better than that in the control group,and the difference was statistically significant(P<0.05).(4)Rank sum test showed that the significant absorption rate of lesions in the observation group after treatment was significantly higher than that in the control group,and the difference was statistically significant(P<0.05).(5)In the observation group,45 cases of sputum turned negative,with a rate of 90.0%;while in the control group,36 cases of sputum turned negative,with a rate of 72.0%,and the difference was statistically significant(P<0.05).(6)The severity of adverse reactions in the o
作者
周婷
尹良胜
马晓卿
郎雅珍
ZHOU Ting;YIN Liangsheng;MA Xiaoqing;LANG Yazhen(Department of Tuberculosis,Zhejiang Integrated Traditional Chinese and Western Medicine Hospital,Hangzhou Red Cross Hospital,Hangzhou 310003,China)
出处
《中国现代医生》
2020年第14期92-95,100,共5页
China Modern Doctor
基金
浙江省中医药科技计划项目(2017ZB076)。
关键词
参苓白术散
肺结核
红细胞沉降率
痰菌转阴率
Shenling Baizhu powder
Tuberculosis
Red blood cell sedimentation rate
Negative conversion ratio
