摘要
痛性糖尿病周围神经病变(PDPN)是糖尿病慢性并发症,其发病机制比较复杂,目前在治疗上无明确疗效的西药。木丹颗粒是益气活血、通络止痛的代表中药复方制剂,在临床上可以从多角度对PDPN起治疗和保护作用。文章就木丹颗粒对PDPN的作用机制及临床疗效做一综述,以期为PDPN的防治策略提供一定依据。
Painful diabetic peripheral neuropathy(PDPN)is a chronic complication of diabetes mellitus.Its pathogenesis is complex.At present,there is no clear therapeutic effect of Western medicine.Mudan granule is a representative compound preparation of traditional Chinese medicine for Invigorating Qi,promoting blood circulation and relieving pain.It can treat and protect PDPN from many aspects.In this paper,the mechanism and clinical effect of Mudan granules on PDPN were reviewed,in order to provide some basis for the prevention and treatment strategy of PDPN.
作者
齐月(综述)
冷锦红(审校)
Qi Yue;Leng Jinhong(Department of Endocrinology, Affiliated Hospital of Liaoning University of TCM, Liaoning Province,Shenyang 110032, China)
出处
《疑难病杂志》
CAS
2020年第7期743-746,共4页
Chinese Journal of Difficult and Complicated Cases
基金
国家自然科学基金项目(81072912)
辽宁省自然科学基金指导计划项目(2017010131-301)
辽宁中医药大学校级课题(2016xj04)。
关键词
痛性糖尿病周围神经病变
木丹颗粒
作用机制
Painful diabetic peripheral neuropathy
Mudan granule
Intervention study