摘要
抗肾小球基底膜病是一种发病率较低,但伴有严重临床症状的自身免疫性疾病。随着诊断技术的发展,临床中发现,部分患者的临床表现及实验室检查结果与典型抗肾小球基底膜病有许多不同之处。此类抗肾小球基底膜病患者发病机制不明,临床表现不典型,给临床诊断带来了一些困难,目前的治疗方法也无统一标准。本文将对非典型抗肾小球基底膜病研究进展作一综述。
Anti-glomerular basement membrane disease is an autoimmune disease with low incidence but severe clinical symptoms.With the development of diagnosis and related technologies,it is found that in patients with anti-glomerular basement membrane disease,the clinical manifestations and laboratory examination results of some patients are different from those of typical patients in the process of clinical diagnosis.The pathogenesis of such patients with anti-glomerular basement membrane disease are not clear and the clinical manifestations are not typical,it brings some difficulties to clinical diagnosis and there is no uniform standard for its treatment at present.This article will review the research progress of atypical anti-glomerular basement membrane disease.
作者
曹裴扬
杨静
卢国元
CAO Pei-yang;YANG Jing;LU Guo-yuan(Department of Nephrology, the First Affiliated Hospital of Soochow University, Suzhou 215006, Jiangsu, China)
出处
《中国临床医学》
2020年第3期524-527,共4页
Chinese Journal of Clinical Medicine
关键词
抗肾小球基底膜病
发病机制
抗肾小球基底膜抗体
治疗方法
anti-glomerular basement membrane disease
pathogenesis
anti-glomerular basement membrane antibody
therapy method
