摘要
目的:探讨绝经后骨质疏松症患者骨折风险与中医体质的相关性。方法:选择上海中医药大学附属曙光医院骨伤科门诊绝经后骨质疏松症患者为研究对象,采用双能X线骨密度仪测量患者腰椎和髋部骨密度,并收集基本信息和骨折风险因子。采用骨折风险评估工具(fracture risk assessment tool,FRAX^TM)计算受试者10年主要部位骨折风险和髋部骨折风险。采用《中医体质分类与判定》调查患者体质类型特点,分析骨折风险与中医体质的相关性。结果:10年主要部位骨折风险概率为(8.37±4.55)%;10年髋部骨折风险概率为(3.37±3.05)%。各体质类型频次分布以阳虚质最多,其次为气虚质、痰湿质、阴虚质、气郁质、血瘀质、湿热质、特禀质、平和质,且多为兼夹体质。在以10年主要部位骨折风险概率为应变量的多元线性回归分析中,未能有变量引入任何回归模型。在以10年髋部风险概率为应变量的多元性回归分析中,痰湿质和气虚质被引入模型。结论:绝经后骨质疏松症患者中阳虚体质最常见,而痰湿质、气虚质对患者髋部骨折风险影响较大。
Objective:To explore the correlation relationship between fracture risk and constitution of TCM in postmenopausal osteoporosis patients.Methods:Patients with postmenopausal osteoporosis treated in Outpatient Department of Orthopedics of Shuguang Hospital Affiliated to Shanghai University of CM were selected as the research subjects.The BMD of lumbar and hip were measured by dual energy X-ray absorptiometry,and the basic information and fracture risk factors were collected.Fracture risk assessment tool(FRAX)was used to calculate the fracture risk of main parts and hip in the subjects within 10 years.The Classification and Judgment of Constitution of TCM scale was used to investigate the characteristics of patients'constitution types and analyze the correlation between fracture risk and constitution of TCM.Results:Within 10 years,the probability of fracture risk(MO)of main parts was(8.37±4.55)%;the probability of fracture risk(HF)of hip was(3.37±3.05)%.In terms of the frequency distribution of each constitution type,yang deficiency constitution was mostly common,followed by qi deficiency constitution,phlegm dampness constitution,yin deficiency constitution,qi depression constitution,blood stasis constitution,damp heat constitution,special constitution,mild constitution,and most of them are mixed constitution.In the multivariate linear regression analysis with the 10-year fracture risk probability of the main parts as the corresponding variable,no variable was introduced into any regression model.Conclusion:Among the postmenopausal osteoporosis patients,yang deficiency constitution is the most common.However,phlegm dampness constitution and qi deficiency constitution have great influence on the risk of hip fracture.
作者
王燕
郭海玲
吴玉云
徐玉萍
WANG Yan;GUO Hai-ling;WU Yu-yun;XU Yu-ping(Shuguang Hospital Affiliated to Shanghai University of CM,Shanghai,China,201203)
出处
《河南中医》
2020年第7期1038-1041,共4页
Henan Traditional Chinese Medicine
基金
国家自然科学基金项目(81774342,81403415,81473703,81674003)
国家重点学科项目(100508)
上海市重中之重临床重点学科项目(2017ZZ02024)
上海申康医院发展中心慢性病综合防治项目(SHDC12015316)
上海市浦东新区卫生系统重点学科群建设项目(PWZXQ2014-10)
上海市科学技术委员会科研计划项目(17401901900,14401933700,17DZ1920202,16401970102)
海派中医流派传承研究基地项目(ZY3-CCCX-1-1003)。
关键词
绝经后骨质疏松症
骨折风险
骨折风险评估工具
中医体质
阳虚质
气虚质
痰湿质
阴虚质
气郁质
血瘀质
湿热质
特禀质
平和质
postmenopausal osteoporosis
fracture risk
fracture risk assessment tool
constitution of TCM
yang deficiency constitution
qi deficiency constitution
phlegm dampness constitution
yin deficiency constitution
qi depression constitution
blood stasis constitution
damp heat constitution
special constitution
mild constitution
