摘要
目的研究长期使用开塞露对排便障碍的影响及可能的机制。方法收集2017年6月至2019年6月在浙江省立同德医院肛肠外科就诊的排便梗阻综合征(ODS)患者63例,其中长期使用开塞露的30例患者纳入观察组,未曾使用或基本不使用开塞露的33例患者纳入对照组。比较两组患者肛门指检、便秘症状评分、排粪造影、盆底肌电图检查结果,并探讨开塞露影响肛门功能的可能机制。结果观察组患者肛门指检提肛肌松弛障碍发生率、排便频率评分、排便费力评分、用力排便相肛直角度数变小发生率均高于对照组,差异均有统计学意义(均P<0.01)。结论便秘患者长期使用开塞露可导致肛肠环(耻骨直肠肌)在用力排便时出现痉挛、僵硬或反常收缩等松弛障碍现象,并加重患者的便秘症状。
Objective To study the effect of long-term use of glycerol enema on defecation disorder and its possible mechanism.Methods Sixty-three patients with obstructive defecation syndrome(ODS)were enrolled in the study,including thirty cases of long-termuse of glycerol enema(observation group)and thirty-three cases of non-users(control group).The results of digital examination,constipation symptomscore,defecography and pelvic floor electromyography were compared between the two groups,and the possible mechanism of glycerol enema affecting anal function was discussed.Results In the observation group,the incidence of relaxation disorder in digital examination of anus,the number of anorectal angle reduction in the force defecation phase were significantly higher than those in the control group,and the scores of defecation frequency and defecation effort were significantly higher than those in the control group(all P<0.01).Conclusion Long-term use of glycerol enema in constipation patients can lead to relaxation disorder such as spasm,rigidity or paraoloxical contraction of anorectum ring(puborectails muscle)during defecation,and aggravate the constipation symptoms of the patients.
作者
崔焌辉
潘治平
金婧
蔡珂
沈锋
吴霜
CUI Junhui;PAN Zhiping;JIN Jing(Department of Colorectal Surgery,Tongde Hospital of Zhejiang Province,Hangzhou 310012,China)
出处
《浙江医学》
CAS
2020年第11期1131-1134,共4页
Zhejiang Medical Journal
关键词
开塞露
排便障碍(便秘)
耻骨直肠肌
反常收缩
Glycerol enema
Defecation disorder(Constipation)
Puborectalis muscle
Paradoxical contraction
