摘要
目的分析50岁以上年龄相关性白内障人群角膜散光与年龄、眼轴长度的关系。方法回顾性系列病例研究。纳入2016年2至8月就诊于北京大学人民医院眼科的50岁以上年龄相关性白内障患者953例(1906只眼)的检查资料,分析患者基本信息及白内障摘除手术前IOLMaster测得的眼轴长度、角膜散光度数及轴向结果。应用限制性立方样条图、Spearman等级相关分析法分析角膜散光度数与年龄的相关性,应用χ2检验分析不同年龄组、眼轴长度组或角膜散光度数分组中角膜散光轴向的分布情况。结果953例(1906只眼)患者中,男性410例,女性543例;顺规散光570只眼(29.91%),逆规散光1005只眼(52.73%),斜轴散光331只眼(17.37%);年龄(72±9)岁;眼轴长度,右眼中位数为23.49 mm(19.83~33.89 mm),左眼中位数为23.41 mm(17.54~32.09 mm);角膜散光度数,右眼中位数为0.97 D(0.06~4.65 D),左眼中位数为0.92 D(0.11~4.88 D)。角膜散光度数≥0.75 D的比例分别为右眼64.95%(619/953),左眼61.59%(587/953)。65岁以上人群及眼轴长度为22.00~25.99 mm时双眼角膜散光度数与年龄呈正相关(r=0.186~0.279,均P<0.01),其中逆规散光度数与年龄正相关(右眼r=0.278,左眼r=0.225;均P<0.01),而顺规散光度数与年龄无明显相关(右眼P=0.335,左眼P=0.633)。随年龄增大,双眼顺规散光比例减少,右眼由43.81%(46/105)降至20.73%(51/246),左眼由40.00%(42/105)降至24.80%(61/246);逆规散光比例增加,右眼由38.10%(40/105)增至61.38%(151/246),左眼由33.33%(35/105)增至58.94%(145/246);而斜轴散光比例基本不变,分布差异有统计学意义(右眼χ2=31.986,左眼χ2=27.686;均P<0.01)。双眼不同眼轴长度组的角膜散光轴向分布差异无统计学意义(右眼P=0.497,左眼P=0.897)。角膜散光度数越大,双眼斜轴散光比例越小,右眼、左眼分别由25.45%(85/334)、29.78%(109/366)减少至0和1.35%(1/74);逆规散光比例越大,右眼由39.82%(133/334)增加至79.27%(65/82),左眼�
Objective To investigate the relationship between corneal astigmatism and age, axial length (AL) in age-related cataract patients over 50 years old.Methods In this retrospective study, 1 906 eyes of 953 patients with age-related cataract were diagnosed from February 2016 to August 2016 atPeking University People′s Hospital, and their demographics, preoperative AL, magnitude and meridian of the corneal astigmatism measured by IOL Master were collected. Restricted cubic splines and Spearman rank correlation coefficients were used to investigate the relationship of the magnitude of cornea astigmatism to age. Chi-square test was used to assess the relationship of the meridian of astigmatism to age, AL and the magnitude of cornea astigmatism.Results The patients were 410 men and 543 women. The corneal astigmatism was with-the-rule (WTR) in 570 eyes (29.91%), against-the-rule (ATR) in 1 005 eyes (52.73%) and oblique in 331 eyes (17.37%). The mean age was (72±9) years old. The medians (min, max) of AL and corneal astigmatism magnitude were 23.49 mm (19.83 mm to 33.89 mm) and 0.97 D (0.06 D to 4.65 D) in right eyes and 23.41 mm (17.54 mm to 32.09 mm) and 0.92 D (0.11 D to 4.88 D) in left eyes, respectively. The corneal astigmatism was ≥0.75 D in 64.95% (619/953) of the right eyes and 61.59% (587/953) of the left eyes. Among the elderly patients over 65 years old, when the AL was between 22.00-25.99 mm (r=0.186-0.279), the value of corneal astigmatism was positively correlated with age (all P<0.01) in both eyes. The value of ATR corneal astigmatism was positively correlated with age (right eyes, r=0.278, P<0.01;left eyes, r=0.225, P<0.01), while the value of WTR corneal astigmatism had no statistically significant correlation with age (right eyes, P=0.335;left eyes, P=0.633). The prevalence of WTR astigmatism decreased with age from 43.81% (46/105) to 20.73% (51/246) in right eyes and from 40.00% (42/105) to 24.80% (61/246) in left eyes, while the prevalence of ATR astigmatism increased with age from 38.10% (40/105)
作者
庞仪琳
元力
曹晓光
侯宪如
鲍永珍
Pang Yilin;Yuan Li;Cao Xiaoguang;Hou Xianru;Bao Yongzhen(Department of Ophthalmology,Peking University People′s Hospital,Eye Diseases and Optometry Institute,Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases,College of Optometry,Peking University Health Science Center,Beijing 100044,China)
出处
《中华眼科杂志》
CAS
CSCD
北大核心
2020年第5期349-355,共7页
Chinese Journal of Ophthalmology
关键词
白内障
老年人
散光
轴长度
眼
年龄因素
Cataract
Aged
Astigmatism
Axial length,eye
Age factors
