摘要
背景与目的早期筛查是有效降低肺癌死亡率的重要方式,然而我国尚缺乏统一、有效的肺癌早期筛查标准与手段。本研究基于四川大学华西医院构建的肺结节/肺癌患者全程管理平台,将肺结节早期筛查纳入肺癌规范诊疗体系,以期实现提升肺癌患者生存率。方法建立三大研究队列:健康人群筛查队列、肺结节患者队列、肺癌患者队列,系统、持续收集、分析各队列人群临床诊疗相关大数据。初步计划对肺结节早期筛查效果进行验证。结果该平台初步以2015年1月1日-2019年12月31日华西医院40岁以上职工2,836人作为实施对象,共诊断66例肺癌,均经外科手术切除确诊为早期肺癌65例,1例肺癌伴脑转移。结论肺结节/肺癌患者全程管理项目可实现肺结节高效筛查、随访与诊疗,未来全程管理模式将全面覆盖华西医疗系统,发挥区域带动作用。
Background and Objective Mortality of lung cancer can be decreased by early screening effectively. However, consistent and proficient standards & methods have not been established in China. This study was based on pulmonary nodules/lung cancer comprehensive management platform established by West China Hospital, Sichuan University. Early screening of pulmonary nodules was integrated into standard healthcare of lung cancer system, aiming to improve survivals of lung cancer patients. Methods Three cohorts were established: healthy populations, pulmonary nodules cohort and lung cancer patients cohort, and related clinical data will be collected and analyzed. Preliminary plan includes verifying effect of pulmonary nodules screening module. Results Pulmonary nodules screening was performed in 2,836 employers(>40 years old) of West China Hospital. Lung cancers were diagnosed in 66 participants, all receiving surgery to remove the lesions. 65 of them were with early stage diseases, 1 with lung cancer and brain metastasis. Conclusion Proficient screening, follow-up and healthcare can be achieved via pulmonary nodules/lung cancer comprehensive management mode, which will be extended all over west China region in future.
作者
刘丹
黄燕
周清华
刘伦旭
车国卫
卢铀
许峰
罗锋
白红利
李为民
Dan LIU;Yan HUANG;Qinghua ZHOU;Lunxu LIU;Guowei CHE;You LU;Feng XU;Feng LUO;Hongli BAI;Weimin LI(Department of Respiratory and Critical Care Medicine,West China Hospital,Sichuan University,Chengdu 610041,China;Health Management Center,West China Hospital,Sichuan University,Chengdu 610041,China;Department of Lung Cancer Center,West China Hospital,Sichuan University,Chengdu 610041,China;Department of Thoracic Surgery,West China Hospital,Sichuan University,Chengdu 610041,China;Department of Thoracic Oncology,West China Hospital,Sichuan University,Chengdu 610041,China;Department of radiology,West China Hospital,Sichuan University,Chengdu 610041,China)
出处
《中国肺癌杂志》
CAS
CSCD
北大核心
2020年第5期299-305,共7页
Chinese Journal of Lung Cancer
基金
国家重点研发项目精准专项精准医疗集成应用示范体系建设项(2017YFC0910004)
四川大学华西医院学科卓越发展1.3.5工程项目肺癌早诊早治体系的研究与应用-华西肺癌登月计划(No.ZYJC18001)资助。
关键词
肺结节
肺癌早期筛查
全程管理
Pulmonary nodules
Early screening
Comprehensive management
