摘要
新型冠状病毒肺炎(COVID-19)已成为全球性的重大疫情,中医药在重大疫情防控过程中发挥了重要作用。基于对COVID-19的认识以及中医药防控路径,以疏风解毒胶囊为例,概述了中医药针对早期干预、阻断病情进展、改善症状、抗炎免疫、抑制"细胞因子风暴"以及辨证分型、发挥配伍优势等方面的思路和研究实践,并提出中药新药研发科学模式建立的设想。
Coronavirus disease 2019(COVID-19)has become a major global epidemic,and traditional Chinese medicine(TCM)has played an important role in the prevention and control of major epidemics.Taking Shufeng Jiedu Capsule as an example,this paper summarized the ideas and research practice of TCM in early intervention,blocking disease progression,improving symptoms,anti-inflammation and immunoregulation,suppressing"cytokine storm",syndrome differentiation and playing the advantages of compatibility based on the understanding of COVID-19.The idea of establishing a scientific model for the research and development of new drugs of TCM was put forward.
作者
张铁军
许浚
申秀萍
韩彦琪
刘静
张洪兵
白钢
刘昌孝
ZHANG Tie-jun;XU Jun;SHEN Xiu-ping;HAN Yan-qi;LIU Jing;ZHANG Hong-bing;BAI Gang;LIU Chang-xiao(State Key Laboratory of Drug Delivery and Pharmacokinetics,Tianjin Institute of Pharmaceutical Research,Tianjin 300462,China;Tianjin Key Laboratory of Quality Marker of Traditional Chinese Medicine,Tianjin Institute of Pharmaceutical Research,Tianjin 300193,China;State Key Laboratory of Medicinal Chemical Biology,College of Pharmacy,Nankai University,Tianjin 300071,China)
出处
《中草药》
CAS
CSCD
北大核心
2020年第9期2273-2282,共10页
Chinese Traditional and Herbal Drugs
基金
国家自然科学基金项目(81830111)
国家自然科学基金项目(81703802)
“中医药现代化研究”重点专项(2019YFC1711200)。
