摘要
髓源抑制细胞(MDSCs)是肿瘤免疫微环境中主要的免疫抑制细胞,能通过多种机制发挥免疫应答并参与肺癌的发生发展,其在肺癌免疫治疗的重要性也日益显现,是近年来研究的热点。全文就近年来髓源抑制细胞MDSCs在肺癌中的研究进展作一概述。
Myeloid suppressor cells are the main immunosuppressive cells in the tumor immune microenvironment. They can play an immune response through a variety of mechanisms and participate in the development of lung cancer. The recent research progress of myeloid suppressor cells in lung cancer is summarized in this article.
作者
李贝
骆莹滨
吴建春
李雁
LI Bei;LUO Ying-bin;WU Jian-chun;LI Yan(Shanghai Hospital of Traditional Chinese Medicine Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200071,China)
出处
《肿瘤学杂志》
CAS
2020年第5期386-390,共5页
Journal of Chinese Oncology
关键词
髓源性抑制细胞
肺癌
免疫靶向治疗
myeloid suppressor cells
lung cancer
immunotargeted therapy
