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血管内皮生长因子在乳腺癌中的表达及临床意义 被引量:3

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摘要 目的探讨血管内皮生长因子(VEGF)在乳腺癌中的表达以及临床意义。方法选取2017年4月~2018年2月收治的乳腺癌患者64例为研究组,并选取同期收治的乳腺良性病变患者18例为对照组,应用快捷免疫组化Max-VisionTM法对两组病变组织中VEGF进行检测。结果研究组VEGF阳性表达率为62.50%,对照组VEGF阳性表达率为0.00%,组间差异有统计学意义(P<0.05);VEGF的阳性表达和乳腺癌患者的组织学类型、肿瘤大小、年龄无关(P>0.05),但和腋淋巴结转移、临床分期、组织学分级密切相关(P<0.05)。结论VEGF参与了乳腺癌发生、发展过程,能够作为对乳腺癌预后以及生物学行为的判定指标。
作者 曹娟
出处 《现代诊断与治疗》 CAS 2020年第1期131-133,共3页 Modern Diagnosis and Treatment
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