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生长抑素、加贝酯联合乌司他丁治疗急性胰腺炎的临床疗效分析 被引量:3

Clinical Efficacy of Somatostatin,Gabelide and Ulinastatin in the Treatment of Acute Pancreatitis
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摘要 目的对生长抑素、加贝酯联合乌司他丁治疗急性胰腺炎的临床疗效进行研究和分析。方法对该院在2016年7月—2019年6月收治的56例急性胰腺炎患者进行回顾性分析,按照临床治疗方法的不同,分为实验组、对照A组、对照B组,给予不同方法治疗。对3组患者的临床治疗效果进行分析,对治疗后的血淀粉酶、白细胞、血钙、血糖、上腹压痛、腹痛恢复缓解的时间进行记录分析。结果对照A组临床治疗有效率为72.22%,对照B组临床治疗有效率为83.33%,实验组临床治疗有效率为95.00%。实验组与对照B组和对照A组分别进行对比分析,组间对比差异有统计学意义﹙P<0.05﹚。对3组患者治疗后血淀粉酶、白细胞、血钙、血糖、上腹压痛、腹痛恢复、缓解时间进行比较分析发现,实验组患者的恢复、缓解时间要明显低于对照A组患者与对照B组,组间对比差异有统计学意义﹙P<0.05﹚。结论在急性胰腺炎的临床治疗中联合使用生长抑素、加贝酯和乌司他丁,能够有效改善患者的临床症状,促进患者各项指标的尽快改善,因此,此用药方法值得在临床实践中进行推广和应用。 Objective To study and analyze the clinical efficacy of somatostatin,gabelide and ulinastatin in the treatment of acute pancreatitis.Methods Retrospective analysis was performed on 56 patients with acute pancreatitis admitted to our hospital from July 2016 to June 2019.According to the different clinical treatment methods,they were divided into experimental group,control group A and control group B,and given different treatment methods.The clinical treatment effect of the three groups of patients was analyzed,and the recovery and remission time of blood amylase,white blood cells,blood calcium,blood glucose,epigastric tenderness and abdomi-nal pain after treatment was recorded and analyzed.Results The effective rate of clinical treatment was 72.22%in control group A,83.33%in control group B,and 95.00%in experimental group.The experimental group was compared with the control group B and the control group A.The difference between the groups was statistically significant﹙P<0.05﹚.After comparing the blood amylase,white blood cells,blood calcium,blood sugar,upper abdominal tenderness,abdominal pain recovery and remission time of the three groups of patients,the recovery and remission time of the experimental group were significantly lower than that of the control group A and control B.The difference between the groups was statistically significant﹙P<0.05﹚.Conclusion In the clinical treatment of acute pancreatitis,the combination of somatostatin,gabeside and ulinastatin can effectively improve the clinical symptoms of patients and pro-mote the improvement of the indicators of patients as soon as possible.Therefore,this drug method is worthy of promotion and application in clinical practice.
作者 杨白婧 付高洁 李美姗 朱洪春 YANG Bai-jing;FU Gao-jie;LI Mei-shan;ZHU Hong-chun(Department of Gastroenterology,the Second Affiliated Hospital of Mudanjiang Medical College,Mudanjiang,Heilongjiang Province,157000 China)
出处 《世界复合医学》 2020年第2期156-158,共3页 World Journal of Complex Medicine
关键词 生长抑素 加贝酯 乌司他丁 急性胰腺炎 Somatostatin Gabelide Ulinastatin Acute pancreatitis
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