摘要
缺血性脑卒中患者往往伴有胃肠出血、微生物群失调、便秘等并发症,而肠道微生物群失调会影响缺血性脑卒中的进展和预后。研究人员发现大脑与肠道之间存在双向通讯,它们之间通过多种机制进行信号传递和交流,称为肠-脑轴或脑-肠轴。目前,缺血性脑卒中与脑-肠轴关系的研究仍处于初期阶段,而深入了解缺血性脑卒中和脑-肠轴之间的潜在关系可能有助于开发治疗缺血性脑卒中的新方法。笔者现围绕缺血性脑卒中和脑-肠轴的相互关系进行综述,以期为缺血性脑卒中的预防和治疗开拓新的思路。
Ischemic stroke patients are often accompanied by complications such as gastrointestinal bleeding,microbiological disorders,and constipation,while intestinal microbiological disorders can affect the progress and prognoses of ischemic stroke.Researchers have found two-way communication between the brain and the intestines,and they communicate with each other through various mechanisms,called gut-brain axis or brain-gut axis.However,researches on ischemic stroke and brain-gut axis are still in its infancy,and further understanding of the potential relation between ischemic stroke and brain-gut axis may be helpful in developing new methods for the treatments of ischemic stroke.This paper reviews the relation between ischemic stroke and brain-gut axis to open up new ideas for preventions and treatments of ischemic stroke.
作者
金晶
刘雨朦
伦志刚
唐逸
何明利
Jin Jing;Liu Yumeng;Lun Zhigang;Tang Yi;He Mingli(Department of Neurology,Lianyungang Hospital Affiliated to Xuzhou Medical University,Lianyungang 222002,China;Lianyungang Clinical Medical School,Nanjing Medical University,Lianyungang 222002,China)
出处
《中华神经医学杂志》
CAS
CSCD
北大核心
2020年第5期514-518,共5页
Chinese Journal of Neuromedicine
基金
国家自然科学基金(81970348)。
