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地塞米松与甲泼尼龙治疗突发性耳聋的疗效对比 被引量:3

Comparison of the Efficacy of Dexamethasone and Methylprednisolone in the Treatment of Sudden Deafness
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摘要 目的比较地塞米松和甲泼尼龙运用于突发性耳聋患者治疗中的临床意义。方法将本医院治疗的70例突发性耳聋患者收入项目资料,选自2017年4月-2019年3月,分组法是抽签法,一组归入35例,试验组采取甲泼尼龙治疗方案,对照组采取地塞米松治疗方案,比对两组突发性耳聋患者临床指标。结果试验组药物治疗有效合计率高于对照组评估指标数据值(P<0.05);试验组药物不良反应合计率对比对照组评估指标数据值,差别并不大(P>0.05);试验组治疗之后听阈值低于对照组评估指标数据值(P<0.05)。结论对突发性耳聋患者实行甲泼尼龙治疗的效果优于地塞米松。 Objective To compare the clinical significance of dexamethasone and methylprednisolone in the treatment of sudden deafness. Methods 70 cases of sudden deafness in our hospital were selected from April 2017 to March 2019. The grouping method was drawing lots. One group was divided into 35 cases. The experimental group was treated with methylprednisolone, while the control group was treated with dexamethasone. The clinical indicators of the two groups were compared. Results The total effective rate of drug treatment in the experimental group was higher than that in the control group(P<0.05);the total rate of adverse drug reactions in the experimental group was not significantly different from that in the control group(P>0.05);the auditory threshold in the experimental group was lower than that in the control group(P<0.05). Conclusion Methylprednisolone is superior to dexamethasone in the treatment of sudden deafness.
作者 李小波 LI Xiaobo(Department of Otolaryngology,People’s Hospital of Qijiang,Chongqing 401420,China)
出处 《中国继续医学教育》 2020年第13期150-152,共3页 China Continuing Medical Education
关键词 地塞米松 甲泼尼龙 突发性耳聋 糖皮质激素 不良反应 听阈 dexamethasone methylprednisolone sudden deafness glucocorticoid adverse reactions hearing threshold
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