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麻杏石甘汤加减对支气管肺炎患儿TNF-α、IL-1β的影响 被引量:2

Effects of Modified Maxing Shigan Decoction on TNF-α and IL-1β in Children with Bronchopneumonia
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摘要 目的研究麻杏石甘汤加减治疗小儿支气管肺炎的应用效果。方法选取苏州市相城区中医医院2017年7月至2019年7月支气管肺炎患儿80例,采用数表法分为对照组与试验组,各40例。对照组行常规西药治疗(氨茶碱与西力欣治疗),试验组单独行麻杏石甘汤加减治疗,比较2组治疗效果。结果试验组临床治疗有效率高于与对照组(P<0.05);试验组退热缓解时间、白细胞恢复正常时间、肺部啰音持续时间、咳嗽次数减少时间、肺部X线恢复时间均短于对照组(P<0.05);试验组患儿肿瘤坏死因子-α(TNF-α)、白细胞介素-1β(IL-1β)指标优于对照组(P<0.05)。结论将麻杏石甘汤加减治疗小儿支气管肺炎,可改善患儿各项症状恢复时间,提升临床治疗效果。 Objective To study the effect of modified Maxing Shigan Decoction(MMSD)on children bronchopneumonia.Methods Totally 80 children with bronchopneumonia from July 2017 to July 2019 in Xiangcheng District Hospital of Traditional Chinese Medicine of Suzhou City were divided into control group and experimental group,40 cases each.The control group was treated with routine Western medicine(aminophylline and cilazin),the experimental group was treated with MMSD,and the therapeutic effects of the two groups were compared.Results The clinical effective rate of the experimental group was higher than that of the control group(P<0.05).In that t group,the remission time of antifebrile fever,the recovery time of leucocyte,the duration of lung rale,the reduction time of cough and the recovery time of lung X-ray were shorter than those in the control group(P<0.05);The index of IL-1β was better than that of control group(P<0.05).Conclusion MMSD can improve the recovery time of children's symptoms and improve the clinical therapeutic effect in treatment of children with bronchopneumonia.
作者 臧文静 ZANG Wenjing(Xiangcheng District Chinese Medicine Hospital,Suzhou,Jiangsu 215155,China)
出处 《大医生》 2019年第24期98-100,共3页 Doctor
关键词 麻杏石甘汤 加减治疗 小儿 支气管肺 maxing shigan decoction addition and subtraction treatment children bronchial pneumonia
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