摘要
目的研究血PCT(降钙素原)在败血症患者中的早期诊断价值。方法抽取2016年8月至2018年8月在我院进行治疗的败血症患者60例作为研究组,另选择同期我院肺炎60例作为对照组,对两组入选者均进行血PCT检测,对比两组入选者血PCT水平、血培养阳性阴性血PCT水平及其他检测情况。结果研究组患者血PCT水平均在1 ng/mL以上,且研究组1~5 ng/mL(38.33%)、>5 ng/mL(61.67%)人数均高于对照组1.67%、0.00%,但在<0.05 ng/mL(0.00%)、0.05~1 ng/mL(0.00%)人数上均少于对照组70.00%、28.33%,阳性水平均超过1 ng/mL,阳性组1~5 ng/mL(64.47%)、>5 ng/mL(35.53%)人数均高于阴性组6.82%、0.00%,研究组在CRP、WBC水平上均高于对照组,但对照组LY水平明显低于对照组,差异显著,P<0.05。结论对于疑似败血病的患者可采取血PCT进行早期诊断,能够明显观察到较大的差异,有利于患者及时进行治疗,改善预后,值得应用。
Objective To study the early diagnosis value of serum PCT(procalcitonin)in septicemia patients.Methods 60 septicemia patients checked from August 2016 to August 2018 in our hospital were selected(research group);60 pneumonia patients were selected(control group).Serum PCT contents were detected;positive and negative detection rate of PCT and other indicators were analyzed.Results The research group had PCT contents above 1 ng/mL.NNT(number need to treat)ratio with PCT contents of 1-5ng/mL and>5 ng/mL(38.33%,61.67%)in the research group was higher than control group(1.67%,0.00%),but NNT ratio with PCT contents of<0.05 ng/mL and 0.05-1 ng/mL(0.00%,0.00%)in the research group was lower than control group(70.00%,28.33%).The positive group had PCT contents above 1 ng/mL;the ratio of positive patients with PCT of 1-5 ng/mL and>5 ng/mL(64.47%,35.53%)was higher than negative patients(6.82%,0.00%);the values of CRP(C-reactive protein)and WBC(white blood count)in the research group were higher than control group while LY(lymphocyte percent)was lower than control group(P<0.05).Conclusion For suspected septicemia patients,the detection of serum PCT can make an early diagnosis,which is good to take the proper therapy and improve patient’s prognosis.It is worthy of clinical application.
作者
罗红辉
刘育良
黄聪
古晓龙
LUO Hong-hui;LIU Yu-liang;HUANG Cong;GU Xiao-long(Department of General Medicine,Meizhou People's Hospital,Meizhou 514031,China)
出处
《中国医药指南》
2020年第12期55-56,共2页
Guide of China Medicine
