摘要
慢性阻塞性肺疾病(COPD)作为呼吸系统的常见疾病,具有较高的发病率及病死率,其实质是气道和肺组织的慢性炎症反应,因此,评价炎症反应程度对评估病情及指导治疗有着至关重要的作用,而目前常用的肺功能及COPD综合评估在反映气道炎症方面都存在片面性。近年来,呼出气一氧化氮作为一种炎性指标在评估气道炎性方面的作用备受关注,目前被广泛应用于哮喘的诊疗中,但在COPD诊治中的应用价值尚不明确。本文就呼出气一氧化氮检测对COPD临床意义的研究进展作一综述。
Chronic obstructive pulmonary disease(COPD) as a common disease of the respiratory system, has a high incidence and mortality, and its essence is the chronic inflammatory response of the airway and pulmonary tissue.Therefore, evaluating the degree of inflammatory response is crucial for assessing the condition and guiding treatment.However, the comprehensive assessment of pulmonary function and COPD currently used is one-sided in reflecting airway inflammation. In recent years, exhaled nitric oxide as an inflammatory index has been paid attention for its important role of assessing airway inflammation. It has been widely used in the diagnosis and treatment of asthma, but its application value in the diagnosis and treatment of COPD is still unclear. This article reviews the research progress of exhaled nitric oxide detection in the clinical significance of COPD.
作者
李智慧
许林
LI Zhi-hui;XU Lin(Department of Respiratory and Critical Care Medicine,the Fifth Affiliated Hospital of Kunming Medical University,Yunnan Province,Gejiu 661000,China)
出处
《中国当代医药》
2020年第10期28-31,共4页
China Modern Medicine
关键词
慢性阻塞性肺疾病
呼出气一氧化氮
肺功能
糖皮质激素
吸烟
Chronic obstructive pulmonary disease
Exhaled nitric oxide
Pulmonary function
Glucocorticoid
Smoking
