摘要
目的:观察了解干燥综合征继发肺间质疾病(SS-ILD)患者的临床特征以及中医证候和高分辨率CT(HRCT)分期之间的关系。方法:回顾性分析SS-ILD患者45例,总结分析患者的临床表现、HRCT特征、中医证候。比较HRCT不同分期的患者在中医证候表现方面的特点。结果:SS-ILD临床症状主要是口干,咽干,眼干,咳嗽,咳痰(量少,难咯出),活动后胸闷、气短。HRCT的表现:非特异性间质性肺炎(NSIP)32例占71.1%;囊性改变15例占33.3%。中医辨证虚证34例占75.6%,实证11例占24.4%。虚证患者中肺脾气虚20例,构成比58.8%。实证患者中湿证6例,构成比54.5%;痰证4例,构成比36.4%。HRCT分期中,虚证在1、2、3期中分别占65.0%、81.8%、92.3%。结论:SS-ILD患者除表现干燥相关症状外,均出现明显的呼吸系统症状。HRCT的影像学表现以NSIP和囊性改变为主。中医辨证以虚证为主,主要的证型是肺脾气虚;实证主要是痰湿证。随着HRCT分期严重程度的加重,虚证出现的比例逐渐增高。
Objective:To observe the clinical characteristics in Sj?gren’s syndrome secondary to interstitial lung disease(SS-ILD)patients,and the relationship between TCM syndromes and HRCT stages.Methods:A retrospective analysis of 45 patients with SS-ILD was performed,and the clinical manifestations,HRCT and TCM syndromes were collected.We also compared the characteristics of TCM syndromes in patients with different stages of HRCT.Results:The main clinical symptoms of SS-ILD were dry mouth,dry pharynx,dry eyes,cough,sputum(with sputum,but less difficult to expectorate),chest tightness and shortness of breath after exercise.With HRCT manifestations:NSIP accounted for 32 cases,71.1%of the total and cystic changes in 15 cases,accounting for 33.3%.Deficiency syndrome(34 cases)accounted for 75.6%in TCM syndrome differentiation and 24.4%in excess syndrome(11 cases).In deficiency syndrome patients,qi deficiency of lung and spleen(20 cases)accounted for 58.8%.There were 6 cases of dampness syndrome(54.5%)and 4 cases of phlegm syndrome(36.4%)in excessive syndrome patients.In HRCT stage,deficiency syndrome patients accounted for 65.0%,81.8%and 92.3%in 1,2 and 3 stages respectively.Conclusion:In addition to dry-related symptoms,SS-ILD patients manifested obvious respiratory symptoms.The imaging findings of HRCT were mainly NSIP and cystic changes.Deficiency syndrome is the main syndrome differentiation in TCM,and with the severity of HRCT classification,the proportion of deficiency syndrome increased.The mainly excessive syndrome is phlegm dampness syndrome,and deficiency syndrome is qi deficiency of lung and spleen.
作者
焦以庆
王玉光
郭丽娅
张宗学
王亚南
刘萌
JIAO Yi-qing;WANG Yu-guang;GUO Li-ya;ZHANG Zong-xue;WANG Ya-nan;LIU Meng(Department of Respiratory Medicine,Beijing Hospital of Traditional Chinese Medicine,Capital Medical University,Beijing 100010,China)
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2020年第2期876-879,共4页
China Journal of Traditional Chinese Medicine and Pharmacy
关键词
干燥综合征继发肺间质疾病
中医
西医
高分辨率CT
临床特征
Sjogren’s syndrome secondary to interstitial lung disease
Traditional Chinese medicine
Western medicine
High resolution CT
Clinical characteristics
