摘要
随着我国非酒精性脂肪性肝病(NAFLD)发病率的不断提高,NAFLD已变成最常见的慢性肝病之一。当前西医治疗该病尚无确切临床疗效的药物,而中医治疗显示出良好的治疗效果,且已有不少中药制剂进入二期、三期阶段。笔者从调节肠道菌群的角度对中药治疗NAFLD进行综述,发现已有研究证明肠道菌群失调与NAFLD的发生发展关系密切,中药有效成分(小檗碱、白藜芦醇、制何首乌总多糖和二苯乙烯苷、黄芩苷等)及中药复方(祛湿化瘀方)均对NAFLD有良好的治疗效果。
With its increasing incidence in China,nonalcoholic fatty liver disease(NAFLD) has become one of the most common chronic liver diseases. At present,there is no drug with definite clinical effect in western medicine for this disease,while Chinese herbal medicine has shown good therapeutic effect,and many Chinese herbal preparations have entered the second and third stages. Staring from the regulation of intestinal flora with Chinese herbal medicine for NAFLD,the authors found that the existing studies have proved that the intestinal dysbacteriosis is closely related to the occurrence and development of NAFLD,and some effective components in Chinese herbs(berberine,resveratrol,polygonum multiflorum thunb,baicalin,etc.) and the compound Chinese herbal prescription(Qushi Huayu prescription) have great therapeutic effect.
作者
王慧超
王晓素
周秉舵
WANG Huichao;WANG Xiaosu;ZHOU Bingduo
出处
《新中医》
CAS
2020年第5期13-16,共4页
New Chinese Medicine
基金
上海市进一步加快中医药事业发展三年行动计划项目(ZY3-JSFC-2-1047)。
关键词
非酒精性脂肪性肝病(NAFLD)
中医药
肠道菌群
肠肝轴
文献综述
Nonalcoholic fatty liver disease(NAFLD)
Chinese herbal medicine
Intestinal flora
Gut-liver axis
Literature review
