摘要
目的了解西安市新生儿维生素D(vitamin D,Vit D)营养现状,为及时有针对性地制定区域化及个体化的Vit D营养干预策略提供理论依据。方法采用横断面现状调查的方法,对2018年9月至2018年10月在陕西省西安市西电集团医院产科住院分娩及在新生儿病房住院的新生儿进行血清25羟维生素D(25-hydroxyvitamin D,25(OH)D)水平测定,按年龄和出生体重、性别分组并进行组间比较,采用多元线性回归分析各因素对血清25(OH)D水平的影响。结果共582例新生儿参与研究,出生后24h内平均血清25(OH)D水平为11.2±3.2ng/mL,为缺乏;Vit D(不足+缺乏+严重缺乏)总体发病率为96.70%(563/582例)。胎龄和出生体重对其影响显著(分别β=2.94,P<0.001和β=7.71,P<0.001),与性别无关(β=-0.003,P>0.05)。结论西安市部分新生儿存在Vit D营养不足,需采取措施改善现状。
Objective To investigate the nutritional status of vitamin D(Vit D)in newborns in Xi′an,and to provide a theoretical basis for timely and targeted formulation of regional and individualized Vit D nutrition intervention strategies.Methods A cross sectional survey was performed in newborns within 24 hours life age at the neonatal department of China Xidian Group Hospital.Serum 25-hydroxyvitamin D(25(OH)D)levels were detected and compared for the mean among groups in accordance with gestational age,birth weight and gender.Multiple linear regression analysis was used to analyze the effect of each factor on serum 25(OH)D levels.A P-value of<0.05 was considered significant.Results A total of 582 newborns were recruited in this study.The average serum 25(OH)D level within 24 hours after birth was 11.2±3.2 ng/ml,which was a deficiency.The overall prevalence of Vit D level abnormality(insufficiency+deficiency+severe deficiency)was 96.70%(563/582 cases).The gestational age and birth weight had a significant effect on Vit D levels(β=2.94,P<0.001 andβ=7.71,P<0.001,respectively),while the gender had no effect(β=-0.003,P>0.05).Conclusion Vit D nutritional deficiency existed in some newborns in Xi′an.Measures need to be taken to improve the status of newborn Vit D deficiency.
作者
王昌燕
蒋银萍
裴怀腾
WANG Changyan;JIANG Yinping;PEI Huaiteng(Neonatal Department of China Xidian Group Hospital,Xi'an 710077,China)
出处
《公共卫生与预防医学》
2020年第1期142-144,共3页
Journal of Public Health and Preventive Medicine
