摘要
目的探讨经颅多普勒微栓子监测在糖尿病脑血管病中的应用效果及对并发症的预测价值。方法选取本院2017年12月~2018年7月收治的2型糖尿病合并脑血管疾病患者80例,按照随机数字表法分为两组,各40例。对照组行头部CT检查,观察组实施本研究经颅多普勒超声检查,比较两组检查等待时间及检查耗时,分析脑微栓子阳性与经颅多普勒检测结果的关系,随访1年,比较两组随访期间发生的并发症情况。结果观察组检查等待时间及检查耗时均显著短于对照组(P<0.05),针对脑动脉硬化和脑动脉狭窄诊断上,出现微栓子阳性者有超过60%患者可通过经颅多普勒检测明确合并脑血管疾病,针对脑动脉分支梗死者,其诊断率达到100%,两组检查方法诊断后,随访1年,发生缺血性脑卒中、心肌梗死、眼底血管栓塞、肾功能不全的比例差异无统计学意义(P>0.05)。结论针对2型糖尿病合并脑血管疾病患者,使用经颅多普勒超声检查,具有耗时短,检查快等优点,尤其针对脑动脉硬化、脑动脉狭窄及脑动脉分支梗死者,其检出脑微血管病变可能性大。
Objective To investigate the effect of transcranial Doppler microemboli monitoring in diabetic cerebrovascular disease and its predictive value for complications.Methods 80 patients with type 2 diabetes mellitus complicated with cerebrovascular disease admitted to our hospital from December 2017 to July 2018 were selected as subjects of this study.The patients were divided into two groups according to the random number table method,40 cases in each group.The control group underwent CT examination of the head,and the observation group performed transcranial Doppler ultrasonography.The waiting time and duration of examination were compared between the two groups.The relationship between positive cerebral microemboli and transcranial Doppler examination results was analyzed.The patients were followed up for 1 year,and the complications of the two groups were compared during the follow-up.Results The waiting time and duration of examination in the observation group were significantly shorter than those in the control group(P<0.05).For the diagnosis of cerebral arteriosclerosis and cerebral artery stenosis,more than 60%of patients with positive microemboli could detect clear combined cerebrovascular diseases through transcranial Doppler,and the diagnosis rate of cerebral artery infarction patients reaches 100%.There was no significant difference in the proportion of ischemic stroke,myocardial infarction,fundus vascular embolism and renal insufficiency between the two groups after diagnosis by examination and one year of follow-up(P>0.05).Conclusion For patients with type 2 diabetes mellitus complicated with cerebrovascular disease,transcranial Doppler ultrasound has the advantages of short time-consuming and quick examination,especially for patients with cerebral arteriosclerosis,cerebral artery stenosis and cerebral artery branch infarction,which is more likely to detect cerebral microvascular lesions.
作者
王雷
WANG Lei(Department of Internal Neurology,Dingzhou People's Hospital,Hebei,Dingzhou 073000,China)
出处
《中国医药科学》
2020年第5期201-203,214,共4页
China Medicine And Pharmacy
关键词
经颅多普勒
微栓子
糖尿病
脑血管病
Transcranial Doppler
Microemboli
Diabetes
Cerebrovascular disease
